The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Mineral-driven pyrolysis chemistry and temperature-dependent pyrolysis of textile wastewater sludge: kinetics, reaction pathways, and char functionality. [PDF]
Singh G, Mishra RK, Kumar N.
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Dissolution and gasification behavior of thermosetting resin in molten alkali hydroxide. [PDF]
Tanaka H, Wajima T.
europepmc +1 more source
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Flow diagnosis in a domestic radiator [PDF]
In UK, domestic heating contributes to about 40% of annual energy consumption. Effective and efficient heating systems are essential to drive the cost of heating down.
Ubbi, Kuldip +3 more
core +1 more source
Combustion-Controlled Thermal Loading and Non-Isothermal Spinel Growth in MgO-Al<sub>2</sub>O<sub>3</sub> Systems under Premixed Strained Syngas/Air Flames. [PDF]
Yu C, Chakrabarty S, Fischlschweiger M.
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Effect of Natural Zeolite Modification Route on the Catalytic Pyrolysis of Post-Consumer Polystyrene Toward Styrene-Rich Liquid Products. [PDF]
Hernandez-Fernandez J +2 more
europepmc +1 more source

