Results 291 to 300 of about 8,249,247 (393)

A young patient with lower limb Ewing's sarcoma experienced a cerebral infarction: A care-compliant case report. [PDF]

Medicine (Baltimore)
Zhang SW, Cao DX.
europepmc   +1 more source

Role of MRI in detecting lower limb incompetent perforator veins

, 2017
B. Soni
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Sufficiency of Isolated Vascularised Fibular Free Flaps for Pediatric Intercalary Lower Limb Reconstruction. [PDF]

JB JS Open Access
Saenz L, Wong KW, Davidge KM, Hopyan S.
europepmc   +1 more source

Effects of Different Sensory-Cognitive Interferences on the Biomechanical Characteristics of the Lower Limb During Walking in Patients with Patellofemoral Pain

Ting Fan, Zeyi Zhang
openalex   +1 more source

Exploring the Perceived Difficulty and Importance of Lower Limb Physical Activities for People With and Without Osteoarthritis: A Discrete Choice Experiment [PDF]

Andrés Pierobon, W Taylor, Richard J. Siegert, Robin Willink, Kim L. Bennell, Kelli Allen, Jackie L. Whittaker, J Pearson, Margo Norton, Jane Clark, Hilal Ata Tay, D. Schiphof, Ben Darlow   +12 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

The Role of Lower Limb Kinetics in Boxing Punches and the Impact of Fatigue on Biomechanical Performance. [PDF]

Bioengineering (Basel)
Stewart C, Cornett R, Baker JS, Gu Y, Dutheil F, Ugbolue UC.   +5 more
europepmc   +1 more source

Physiotherapists’ User Acceptance of a Lower Limb Robotic Exoskeleton in Specialized Rehabilitation: Qualitative Exploratory Study (Preprint)

Anstein Olimb Hillkirk, Kirsti Skavberg Roaldsen, Hege Mari Johnsen   +2 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source