Results 211 to 220 of about 5,832,881 (291)

Serum Lipidomics Profiling Identify Novel Biomarkers of Distal Symmetrical Polyneuropathy in Type 1 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10670-10682, November 2026.
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk, Tina Okdahl, Marietta Kokla, Tommi Suvitaival, Gurjeet Kaur, Ismo M. Mattila, Simon M. Kienle, Christian Buhl, Knud Yderstræde, Troels S. Jensen, Peter Rossing, Flemming Pociot, Birgitte Brock, Cristina Legido‐Quigley, Páll Karlsson, Christian S. Hansen, Christina Brock, Joachim Størling, Karolina Sulek   +18 more
wiley   +1 more source

Longitudinal Study of Quality of Life in Individuals with Lower Limb Amputation. [PDF]

Prog Rehabil Med
Nakamura T, Tobimatsu Y.
europepmc   +1 more source

“Life and Lower Limb Threatening Condition” Clinical Features, Management and Outcomes of Diabetic Foot Ulcers Complicated by Gas Gangrene: A Prospective Cohort Study

International Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Diabetic foot ulcer (DFU) is a common complication of diabetes in low‐ and middle‐income countries and may be complicated by gas gangrene (GG), a rapidly progressive, life‐threatening infection. This prospective study assessed whether GG can be diagnosed clinically in low‐resource primary care and explored factors associated with wound‐healing
Zulfiqarali G. Abbas, Raidah R. Gangji, Roozbeh Naemi   +2 more
wiley   +1 more source

Accelerated Preoperative Wound Bed Preparation Using Negative Pressure Wound Therapy With Instillation and Dwell Time: A Comparison With Conventional Negative Pressure Wound Therapy in Necrotic Wounds

International Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Negative pressure wound therapy with instillation and dwell time (NPWTi‐d) and conventional NPWT are established treatments for complex wounds, yet direct comparative evidence remains limited. This retrospective observational study evaluated the clinical effectiveness of NPWTi‐d for hard‐to‐heal necrotic wounds using standardized parameters ...
Norihiko Ohura, Daisuke Nakayama, Mikio Kinoshita, Tomohide Shiraishi, Yuki Morishige, Shungo Murai, Mine Ozaki   +6 more
wiley   +1 more source

Clinical Diagnosis Versus Plain Radiography for Diabetic Foot Osteomyelitis: A Prospective Study of Diagnostic Agreement in a Resource‐Limited Settings

International Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Diabetic foot osteomyelitis (DFO) is a serious complication of diabetic foot ulcers, particularly in advanced infections. In low‐resource settings, access to medical imaging may be limited. This study evaluated the diagnostic agreement between a composite clinical approach (clinical assessment plus probe‐to‐bone test) compared with plain ...
Zulfiqarali G. Abbas, Raidah R. Gangji, Roozbeh Naemi   +2 more
wiley   +1 more source

Prescription of prosthetic ankle-foot mechanisms after major lower limb amputation. [PDF]

Cochrane Database Syst Rev
Vanicek N, Huang C, Davie-Smith FC, Barnett CT, van Oorschot W, van Ee RF, Hofstad CJ.   +6 more
europepmc   +1 more source

Rehabilitation Wearable Boots and Offloading Methods for Diabetic Foot Ulcer Treatment: A Systematic Review

International Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Diabetic foot ulcers (DFUs) are a serious and common complication of diabetes, primarily affecting the plantar surface and toes. They are associated with high rates of recurrence, amputation and mortality, making effective treatment strategies essential.
Yaser Sabzehmeidani, Andrei‐Alexandru Popa   +1 more
wiley   +1 more source

Reamputation risk and mortality after lower-limb amputation in patients with diabetes: predictors, effects of antidiabetic medications and temporal trends. [PDF]

Cardiovasc Diabetol
Radlinger B, Blasinger J, Köllenberger N, Streitberger V, Kopp L, Bifano E, Landolfo M, Aziz F, Sourij H, Göbel G, Klocker J, Kaser S.   +11 more
europepmc   +1 more source

What Is the Evidence for Silver Resistance in Chronic Wounds? A Systematic Review of Prevalence and In Vitro Studies

International Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Silver‐containing wound dressings are among the most widely used topical antimicrobial interventions in chronic wound management. Amid escalating antimicrobial resistance and increasing scrutiny of antiseptic stewardship, there is growing debate regarding the prevalence and clinical relevance of bacterial resistance to silver, yet the ...
Michael Radzieta, Peta Tehan, Emma Bergamin, Saskia Schwarzer, Erik Nygren, Tina Hamberg   +5 more
wiley   +1 more source

Walking speed and sound limb loading are related to femoral cartilage thickness but not cartilage deformation in those with traumatic lower-limb amputation. [PDF]

Osteoarthr Cartil Open
Garcia SA, Nikoumanesh N, Sudhir S, Foucher KC, Hannigan LS.   +4 more
europepmc   +1 more source