Results 61 to 70 of about 3,463,055 (263)

Tight analyses for subgradient descent I: Lower bounds

Open Journal of Mathematical Optimization
Consider the problem of minimizing functions that are Lipschitz and convex, but not necessarily differentiable. We construct a function from this class for which the $Tþ$ iterate of subgradient descent has error $\Omega (\log (T)/\sqrt{T})$. This matches
Harvey, Nicholas J. A., Liaw, Chris, Randhawa, Sikander   +2 more
doaj   +1 more source

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews, Bruce Goodwin, Lauren Buckley, Rick Walker   +3 more
wiley   +1 more source

On second order periodic boundary-value problems with upper and lower solutions in the reversed order

Electronic Journal of Differential Equations, 2006
In this paper, we study the differential equation with the periodic boundary value $$displaylines{ u''(t)=f(t, u(t), u'(t)),quad tin [0, 2pi]cr u(0)=u(2pi), quad u'(0)=u'(2pi).
Haiyin Gao, Shiyou Weng, Daqing Jiang, Xuezhang Hou   +3 more
doaj  

A review of higher order aberrations of the human eye

African Vision and Eye Health, 2019
Background: This literature review is part of a research study for aberration-correcting soft contact lenses, where wavefront aberrometry was utilised.
Ayesha Suliman, Alan Rubin
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

On Higher-Order Nonlinear Fractional Elastic Equations with Dependence on Lower Order Derivatives in Nonlinearity

Fractal and Fractional
The paper studied high-order nonlinear fractional elastic equations that depend on low-order derivatives in nonlinearity and established the existence and uniqueness results by using the Leray–Schauder alternative theorem and Perov’s fixed point theorem ...
Yujun Cui, Chunyu Liang, Yumei Zou
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Hyperedge prediction and the statistical mechanisms of higher-order and lower-order interactions in complex networks. [PDF]

Proc Natl Acad Sci U S A, 2023
Sales-Pardo M, Mariné-Tena A, Guimerà R.   +2 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source