Do clinical findings in lower respiratory tract infection help general practitioners prescribe antibiotics appropriately? An observational cohort study in general practice [PDF]
Rogier Hopstaken +6 more
openalex +1 more source
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Diagnostic efficacy of targeted next-generation sequencing in suspected lower respiratory tract infections of patients with cancer: a retrospective study. [PDF]
Fan X +8 more
europepmc +1 more source
FREQUENT EMPIRIC BROAD‐SPECTRUM ANTIMICROBIAL USE AMONG HOSPITALIZED PATIENTS WITH LOWER RESPIRATORY TRACT INFECTION IN SOUTHERN SRI LANKA [PDF]
openalex +1 more source
Metagenomic insights into respiratory viral signatures in lower respiratory tract infections with and without respiratory failure. [PDF]
Zhu N +6 more
europepmc +1 more source
Objective We evaluated serious infection risk in offspring exposed to tumor necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011–2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman +6 more
wiley +1 more source
Health disparities in complicated lower respiratory tract infections: a population-based cohort study in The Hague, The Netherlands. [PDF]
van Dokkum ED +11 more
europepmc +1 more source
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi +12 more
wiley +1 more source
Targeted next-generation sequencing for pediatric lower respiratory tract infections: a retrospective study. [PDF]
Li L +5 more
europepmc +1 more source
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles +7 more
wiley +1 more source

