Results 221 to 230 of about 6,658,435 (302)

Diagnostic value of procalcitonin for identifying the etiology of lower respiratory tract infections: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Lin CY, Zhou X, Li GG, Qiu J, Li D, Pang QY.   +5 more
europepmc   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Piperacillin/tazobactam plus erythromycin improves clinical outcomes in AECOPD with bacterial lower respiratory tract infections: a retrospective cohort study. [PDF]

Sci Rep
Yang Y, Zhang T, Zheng X, Lu Y, Qu D, Zhu Z, Liu X, Wang J, Ma F, Yang T.   +9 more
europepmc   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Global burden of influenza lower respiratory tract infections in children younger than 5 years from 1990 to 2021. [PDF]

J Thorac Dis
Zhang F, Wu X, Yu N, Huang X, Zhao J.
europepmc   +1 more source

From Evidence to Delivery: Building Readiness for Maternal Respiratory Syncytial Virus Vaccination in Bangladesh

Health Care Science, EarlyView.
Ridwana Maher Manna, Siobhan L. Johnstone, Pradip Chandra, Michelle J. Groome, Shams El Arifeen, Aniqa Tasnim Hossain   +5 more
wiley   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao, Yinfeng Guo, Shaoyan Xu, Min Zhang, Yanxia Rui, Shujun Pan, Changhua Zhou, Jianxiang Chen, Henglan Wu   +8 more
wiley   +1 more source

The bacterial etiology and antimicrobial susceptibility of lower respiratory tract infections in Vietnam. [PDF]

Ann Clin Microbiol Antimicrob
Dung TTN, Vinh C, Anh PH, Linh VKP, Tuyen HT, Tam PT, Lan NPH, Phu TT, Tuyet NSM, Nhung PH, Trang VD, Van NT, Nguyen Q, Thanh NT, Kesteman T, van Doorn HR, Thwaites G, Duy PT.   +17 more
europepmc   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Low‐Level Human Epididymis Protein 4 in Seminal Plasma Is an Independent Risk Factor for Poor Semen Liquefaction: A Case Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Our work identifies a novel and significant association between low seminal levels of Human Epididymis Protein 4 (HE4) and the clinical condition of poor semen liquefaction, a common cause of male infertility. The findings are statistically robust, clinically relevant, and provide a foundational basis for future research into the mechanism by which HE4
Feifei Wang, Jiangnan Wu, Shijie Gao, Zhuohan Zheng, Zhiheng Wang, Jing Gao   +5 more
wiley   +1 more source