Results 251 to 260 of about 601,448 (407)

Peptides Corresponding to the Receptor‐Binding Domain (RBD) of Several SARS‐CoV‐2 Variants Of Concern Prevent Recognition of the Human ACE2 Receptor and Consecutive Cell Infections

open access: yesChemMedChem, Volume 20, Issue 7, April 1, 2025.
Despite the end of the COVID‐19 pandemic, SARS‐CoV‐2 will remain a constant factor in our lives. For this reason, the development of new preventive therapeutics is necessary. Here, the first steps were taken by testing peptides for their inhibitory activity on the binding between the human ACE‐2 receptor and the RBD of the virus.
Mandy Schwarze   +3 more
wiley   +1 more source

Infections of the lower respiratory tract

open access: yes, 2010
Robert C. Read, Lionel A. Mandell
openaire   +2 more sources

Predictors of Short-Term Functional Decline in Survivors of Nursing Home-Acquired Lower Respiratory Tract Infection [PDF]

open access: bronze, 2003
Ellen F. Binder   +6 more
openalex   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou   +6 more
wiley   +1 more source

Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis. [PDF]

open access: yesAntibiotics (Basel)
Reyes LF   +39 more
europepmc   +1 more source

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis

open access: yes
Cancer Communications, EarlyView.
Lea Järke   +15 more
wiley   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

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