Results 31 to 40 of about 274,467 (306)

Grepafloxacin Clinical Program for Lower Respiratory Tract Infections

Canadian Journal of Infectious Diseases, 1998
The present paper evaluates the clinical trial program in lower respiratory tract infections treated with a new fluoroquinolone antibiotic, grepafloxacin.
Arne C Rodloff
doaj   +1 more source

Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice research database

, 2007
Objective: To determine the extent to which antibiotics reduce the risk of serious complications after common respiratory tract infections. Design: Retrospective cohort study.
Johnson, A. M., Livermore, D. M., Hayward, A.C., Livermore, D.M., Islam, A., Petersen, I., Duckworth, G., Johnson, A.M., Peterson, I., Hayward, A. C.   +9 more
core   +1 more source

Morbi-mortality of lower respiratory tract infections in Spain, 1997-2018

Anales del Sistema Sanitario de Navarra, 2021
Background. Lower respiratory tract infections (LRTIs) are one of the leading causes of infectious disease mortality worldwide. The aims of the study were to determine the incidence of hospitalizations due to LRTIs, and to analyze the clinical outcomes ...
L. Leache, M. Gutiérrez-Valencia, L.C. Saiz, J. Erviti   +3 more
doaj   +1 more source

New Antibiotics for Lower Respiratory Tract Infections

Microbiology Research
Respiratory tract infections are frequently encountered in clinical practice. The growing incidence of antimicrobial resistance among the causative pathogens exerts sustained pressure on the existing therapeutic options.
Despoina Papageorgiou, Maria Gavatha, Dimitrios Efthymiou, Eleni Polyzou, Aristotelis Tsiakalos, Karolina Akinosoglou   +5 more
doaj   +1 more source

Viral etiologies of lower respiratory tract infections in children < 5 years of age in Addis Ababa, Ethiopia: a prospective case–control study

Virology Journal, 2023
Background Lower respiratory tract infections (LRTIs) are a major cause of morbidity and mortality in children worldwide and disproportionally affect Sub-Saharan Africa.
Fiseha Wadilo, Adey Feleke, Meseret Gebre, Wude Mihret, Tamrayehu Seyoum, Kalkidan Melaku, Rawliegh Howe, Andargachew Mulu, Adane Mihret   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Isolation and Identification of Bacteria Associated with Lower Respiratory Tract Infection among Patients Attending General Hospital Katsina

UMYU Journal of Microbiology Research, 2017
Lower respiratory tract infections (LRTIs) have been one of the major causes of morbidity and mortality worldwide. Routine diagnosis of LRTIs in our hospitals does not include adequate and extensive identification of these organisms ...
Usman, A. D., Amina Muhammad
doaj   +1 more source

The Diagnostic Value of Metagenomic Next–Generation Sequencing in Lower Respiratory Tract Infection

Frontiers in Cellular and Infection Microbiology, 2021
Lower respiratory tract infections are associated with high morbidity and mortality and significant clinical harm. Due to the limited ability of traditional pathogen detection methods, anti-infective therapy is mostly empirical.
Yan Zheng, Xiaojian Qiu, Ting Wang, Jie Zhang   +3 more
doaj   +1 more source

Tools for detection of Mycoplasma amphoriforme : a primary respiratory pathogen?

, 2014
This work was supported by a Peter Samuel Royal Free Fund grant, the Primary Immunodeficiency Association, the Special Trustees of the Royal Free London NHS Foundation Trust, Hampstead, and the University of St.
Oravcova, Katarina, McHugh, Timothy D., Dilworth, Paul, Munro, Michelle, Templeton, Kate, Beattie, Thomas F., Ling, Clare L., Webster, David, McHugh, Timothy, Hardie, Alison, Pond, Marcus, Fulton, Naomi L., Gillespie, Stephen Henry, Workman, Sarita, Gillespie, Stephen H., Creer, Dean D., Beattie, Thomas Ferris   +16 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source