Results 71 to 80 of about 259,922 (311)

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

Clinical Aspects of Upper and Lower Respiratory Tract Infections [PDF]

, 1993
Ronald F. Grossman
openalex   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

Advanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong, Pietro Cataldi, Han Zhang, Emiliano Bilotti, Conor Boland, Athanassia Athanassiou, Dimitrios G. Papageorgiou   +6 more
wiley   +1 more source

Evaluation of an automated analytical system for rapid screening of lower respiratory tract infections

Microbiologia Medica, 2012
Respiratory tract infections are relevant causes of morbidity and mortality. It has been demonstrated that an appropriate initial antimicrobial regimen, or its early modification based on microbiological results, leads to a higher survival rate ...
Shamanta Grosso, Graziano Bruschetta, Laura Favero, Marisa Gobbo, Paola Zigante, Alessandro Camporese   +5 more
doaj   +1 more source

Reassessment of a meta-analysis of procalcitonin-guided antibiotic therapy for lower respiratory tract infections [PDF]

, 2018
Aarati Keshary, Robert G. Badgett
openalex   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

2224. Reducing Antibiotic Overuse in Adult Lower Respiratory Tract Infections Using Novel Host–Response-Based Diagnostics [PDF]

, 2019
Liran Shani, Salim Halabi, Shachaf Shiber, Meital Paz, Einat Moscoviz, Ami Neuberger, Neta Petersiel, Mordechai Grupper, Dani Kirshner, Daniel A. Haber, Gali Kronenfeld, Niv Mastboim, Tanya Gottlieb, Michal Stein, Nurit Rudich, Naama Sitry, Claire S Guetta, Ester Pri-Or, Ynon Lishtzinsky, Shirly Yanai, ‪Yasmin Maor‬‏, Kfir Oved, Eran Eden, Michael J. Drescher, Mical Paul   +24 more
openalex   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

T-Cell Profiles In Bronchoalveolar Lavage (BAL) Of Wheezing Children With and Without A History Of Respiratory Syncytial Virus (RSV) Lower Respiratory Tract Infection [PDF]

, 2014
Chang-Kuen Kim, Jin-Tack Kim, Sally E. Wenzel, Marzena Krawiec   +3 more
openalex   +1 more source