Results 71 to 80 of about 274,467 (306)

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Parental engagement in research on paediatric lower respiratory tract infections in Indonesia

BMC Pediatrics
Background Lower respiratory tract infections (LRTIs) in children are a major concern in Indonesia as it is the leading cause of morbidity and mortality. Therefore, research on LRTIs is crucial to improve children’s health.
Vincentia Rizke Ciptaningtyas, Tanjung Ayu Sumekar, Quirijn de Mast, Marinus Isaäk de Jonge, Ani Margawati   +4 more
doaj   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

Advanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal, Kai‐Po Fan, Sheng‐Chun Hung, Jaba Roy Chowdhury, Jun‐Hsun Chung, Meenakshi Ray, Hsiang‐Yun Hsu, Fu‐Cheng Kao, Kuei‐Lin Liu, Zong‐Hong Lin   +9 more
wiley   +1 more source

ETIOLOGY, CLINICAL MANIFESTATIONS, AND AGE CHARACTERISTICS OF MIXED VIRAL RESPIRATORY INFECTIONS WITHIN 2024-2025

Problems of Infectious and Parasitic Diseases
Introduction: This study aims to investigate mixed viral respiratory infections, examining their causes, age patterns, and the involvement of co-pathogens in the lower respiratory tract infections (LRTIs).
Dyana Pavlova, Ivelina Trifonova, Neli Korsun, Petar Velikov, Ivan Ivanov, Daniel Ivanov, Trifon Valkov, Iva Christova   +7 more
doaj   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Understanding parental consent and trust in paediatric LRTI research: insights from a qualitative study in Indonesia

BMC Public Health
Background Scientific research is essential to reduce the burden of paediatric lower respiratory tract infections (LRTI), one of the leading causes of death in children under five years of age in Indonesia.
Vincentia Rizke Ciptaningtyas, Tanjung Ayu Sumekar, Lathifa Putry Fauzia, Quirijn de Mast, Marinus Isaäk de Jonge, Ani Margawati   +5 more
doaj   +1 more source

Single and multiple viral infections in lower respiratory tract infection [PDF]

, 2010
Lower respiratory tract infection (LRTI) often leads to hospitalization, and it was indicated that causative viral infections are ...
Stolz, Daiana, Daiana Stolz, Mikael Gencay, Michael Roth, Mueller, Beat, Gencay, Mikael, Tamm, Michael, Beat Mueller, Michael Tamm, Roth, Michael, Christ-Crain, Mirjam, Mirjam Christ-Crain   +11 more
core   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, EarlyView.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Practice patterns for lower respiratory tract infections in hospital patients with particular focus on bacteriological examinations and injection antibiotics use

International Journal of General Medicine, 2013
Mikio Wada,1 Takeo Nakayama,2 Tatsuro Ishizaki,3 Toshihiko Satoh,4 Shunya Ikeda51General Internal Medicine, Fukuchiyama City Hospital, Fukuchiyama, Kyoto, Japan; 2Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan ...
Wada M, Nakayama T, Ishizaki T, Satoh T, Ikeda S   +4 more
doaj  

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source