Results 181 to 190 of about 6,050,843 (300)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Lacking a vocational upper-secondary diploma: motivational and proximal contextual predictors in primary and lower-secondary education. [PDF]

Empir Res Vocat Educ Train
Hofmann J, Neuenschwander MP, Ramseier L.   +2 more
europepmc   +1 more source

Accumulated Disadvantage over the Lower Secondary School Years in Helsinki Metropolitan Area, Finland. [PDF]

Int J Environ Res Public Health, 2020
Karvonen S, Kestilä L, Rimpelä A.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Mental health in student-athletes in Norwegian lower secondary sport schools. [PDF]

BMJ Open Sport Exerc Med
Saarinen M, Phipps DJ, Bjørndal CT.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Mapping lower secondary school students' conceptions of three aspects critical for understanding the nervous system. [PDF]

PLoS One
Kvello P.
europepmc   +1 more source

Testing a physical education-delivered autonomy supportive intervention to promote leisure-time physical activity in lower secondary school students: the PETALS trial. [PDF]

BMC Public Health, 2020
Schneider J, Polet J, Hassandra M, Lintunen T, Laukkanen A, Hankonen N, Hirvensalo M, Tammelin TH, Törmäkangas T, Hagger MS.   +9 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Effects of the Informed Health Choices secondary school intervention on the ability of lower secondary students in Kenya to think critically about health choices: 1-year follow-up of a cluster-randomized trial. [PDF]

Trials
Chesire F, Kaseje M, Gisore V, Mugisha M, Ssenyonga R, Oxman M, Nsangi A, Semakula D, Rose CJ, Nyirazinyoye L, Lewin S, Sewankambo NK, Rosenbaum S, Moberg J, Oxman AD.   +14 more
europepmc   +1 more source