Results 101 to 110 of about 175,224 (302)

Evaluation of the Lower Urinary Tract Symptoms and Erectile Dysfunction with Uroflowmetry, IPSS and IIEF Questioniares

open access: yes, 2015
Objective This study was conducted to investigate the relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in aging men. The population of elderly men in Turkey has increased through last two decades.
Erem Kaan Başok   +2 more
core   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi   +6 more
wiley   +1 more source

The challenges of lower urinary tract symptoms in men

open access: yesCanadian Urological Association Journal, 2012
Two distinct urologic entities were discussed in depth at the 2nd Annual Canadian Urology Forum (2012): stress urinary incontinence (SUI) in women; and lower urinary tract symptoms (LUTS) in men. The LUTS component of the educational program included a distinguished panel of Canadian and international experts, who collaborated to present and discuss
Greg, Bailly, J Curtis, Nickel
openaire   +3 more sources

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola   +14 more
wiley   +1 more source

Understanding mechanisms of Ketamine-induced human urinary tract damage [PDF]

open access: yes, 2011
Ketamine is a phencyclidine derivative N-Methyl D-Aspartate (NMDA) receptor antagonist used as an anaesthetic and analgesic. A florid non-bacterial cystitis condition known as ketamine-induced cystitis (KIC) has recently been reported in abusers and ...
Shahzad, Khurram
core  

Lower urinary tract symptoms and falls risk among older women receiving home support: A prospective cohort study.

open access: yes, 2013
Background Although lower urinary tract symptoms have been associated with falls, few studies have been undertaken to understand this relationship in vulnerable community dwelling older adults.
Hsu, Z. Y.   +3 more
core   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher   +12 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 CAR‐T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T‐cell therapy in patients with progressive systemic sclerosis. Methods Patients with progressive systemic sclerosis received CD19 CAR‐T cell therapy and were followed longitudinally for safety, clinical efficacy, immune ...
Chenhan Jia   +16 more
wiley   +1 more source

Changes in lower urinary tract symptoms after prostate brachytherapy

open access: yes, 2011
Purpose: To further define the bothersome lower urinary tract symptoms that occur after prostate brachytherapy(PB) by evaluating patient’s responses to the individual questions of the urinary portion of the Expanded Prostate CancerIndex Composite (EPIC ...
Ryan P. Smith   +3 more
core  

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