Results 91 to 100 of about 655,560 (301)

The effect of post-amputation pain on health-related quality of life in lower limb amputees

open access: yesDisability and Rehabilitation, 2020
There is conflicting literature on the effect of post-amputation pain on quality of life (QOL) and no available literature on the relationship of pain medications to QOL of amputees in pain. The aims of the study were to compare QOL in lower limb amputees with significant pain to those with minimal pain and compare QOL in amputees on multiple pain ...
N. Gupta, C. Leung
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Is robotic hepatectomy cost-effective? In view of patient-reported outcomes

open access: yesAsian Journal of Surgery, 2019
Summary: Background: Robotic hepatectomy has been accepted as an alternative for patients needing surgery. However, few reports addressed the patient-reported outcomes and long-term quality of life (QoL) of patients having undergone robotic liver ...
Chao-Ying Wu   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Dyslipidaemia in elderly and stroke patients

open access: yesIndian Heart Journal
Lowering of cholesterol containing atherogenic particles through lipid lowering therapies is of outmost important in both in the elderly age group and younger age group in reducing the cardiovascular risk.
Dhiman Kahali
doaj   +1 more source

Quality of life of people with Parkinson’s disease in the context of professional work and physiotherapy

open access: yesMedycyna Pracy, 2017
Background: Of many diseases and disorders of the nervous system Parkinson’s disease (PD) deserves a particular attention for its specific effects having an impact on the ability to undertake different forms of professional and economic activities.
Joanna Cholewa   +3 more
doaj   +1 more source

Effects of Customer Services Efficiency and Market Effectiveness on Dealer Performance [PDF]

open access: yes
Market orientation is positively associated with performance of dealers in terms of customer service quality, growth in sales and increase in market share.
Rajagopal
core  

Getting research findings into practice : when to act on the evidence. [PDF]

open access: yes, 1998
There is increasing interest in providing evidence based health care—that is, care in which healthcare professionals, provider managers, those who commission health care, the public, and policymakers consistently consider research evidence when making ...
Guyatt, G H, Haines, A, Sheldon, T A
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Health-related quality of life in obese youth in the lower Mississippi Delta

open access: yesOpen Journal of Preventive Medicine, 2012
Objective: Adults and children in rural settings are at greater risk for overweight and obesity than those in urban settings. Multiple studies have suggested that quality of life is lower for obese individuals. This study addresses the association of obesity with health-related Quality of Life (QOL) among youth in the rural Mississippi Delta.
Wendy L. Ward   +5 more
openaire   +2 more sources

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