Results 21 to 30 of about 5,097 (243)

Experimental and numerical investigation of energy absorption in honeycomb structures based on lozenge grid unit cells under various loading angles

Composites Part C: Open Access
The present study aims to numerically and experimentally analyze the energy absorption characteristics of honeycomb structures using Lozenge grid unit cells made from continuous glass fibers reinforced polylactic acid (PLA).
Hussain Gharehbaghi, Maryam Jamshidi, Abdulla Almomani   +2 more
doaj   +1 more source

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Ambroxol Hard-Boiled Lozenges in Patients with Acute Pharyngitis

Pulmonary Therapy, 2019
Introduction The aim of this study was to evaluate the efficacy and safety of a new hard-boiled lozenge formulation containing ambroxol 20 mg versus placebo for the relief of sore throat in patients with acute pharyngitis.
Rita Sousa, Deepak R. Lakha, Sandrine Brette, Simon Hitier   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Parsimony and complexity: Cell fate assignment in the developing Drosophila eye

Fly, 2017
The specification of the R7 photoreceptor in the Drosophila eye has become a classic model for understanding how cell fates are assigned in developing systems.
Yannis Emmanuel Mavromatakis, Andrew Tomlinson   +1 more
doaj   +1 more source

On innovations of n-dimensional integral-type inequality on time scales

Advances in Difference Equations, 2021
Integral-type inequalities and dynamic equations have an important place in time scales. In this paper, we present some innovations of n-dimensional Minkowski’s integral-type inequality on time scales via ◊ α $\lozenge _{\alpha } $ -integral.
Lütfi Akın
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

A systematic review of flurbiprofen 8.75 mg dose and risk of adverse events (excluding haemorrhagic) resulting from drug-drug interactions

Frontiers in Pharmacology
Background: Flurbiprofen 8.75 mg lozenges and oromucosal sprays are used for symptomatic relief of sore throat in patients aged 12 years and over. The documented adverse events of flurbiprofen use include those related to its pharmacological actions ...
Alison Evans, Alison Evans, Debabrata Roy, Debabrata Roy, Sandeep Dhanda, Sandeep Dhanda, Samantha Lane, Samantha Lane, Graça Coutinho, Anuradha Kulasekaran, David Miller-Shakesby, Nagalakshmi Ramamoorthi, Saad Shakir, Saad Shakir   +13 more
doaj   +1 more source

Bilateral anterior lenticonus in Alport syndrome

Kerala Journal of Ophthalmology, 2023
Anterior lenticonus is a structural anomaly of the crystalline lens characterized by a localized conical or spherical protrusion centered about the pole of the anterior lens surface.
Nirupama Kasturi, T Doris Benita
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source