eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
Assessment of cone-beam CT technical image quality indicators and radiation dose for optimal STL model used in visual surgical planning. [PDF]
Koivisto J +7 more
europepmc +1 more source
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang +8 more
wiley +1 more source
Can a low-threshold check-up motivate older adults to schedule a dental visit? Study protocol for a randomized controlled trial. [PDF]
De Vleeschauwer A +3 more
europepmc +1 more source
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi +12 more
wiley +1 more source
Combining motor competence and motor learning strategies helps to reduce the risk of biomechanical factors associated with ACL injury. [PDF]
Orangi BM +3 more
europepmc +1 more source
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo +7 more
wiley +1 more source
Helmet-Head Decoupling in Ice Hockey Impacts: An In-lab Exploratory Study Using Autoregressive Modeling of Acceleration Data Measured from a Helmet-Mounted Inertial Measurement Unit (IMU). [PDF]
Sciacca D, Ionescu A.
europepmc +1 more source
ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng +19 more
wiley +1 more source
What Lies Behind Diagnostic Labels? High Intra-Individual Variability Is the True Cognitive Signature of University Students with Specific Learning Disorders. [PDF]
Zonca S, Bizzaro ML, Girelli L.
europepmc +1 more source

