Results 141 to 150 of about 922,792 (334)

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

open access: yesAdvanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung   +6 more
wiley   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa   +5 more
wiley   +1 more source

Inclusion mappings between lp spaces

open access: yesJournal of Functional Analysis, 1973
AbstractIt is shown that the inclusion mapping from lpinto lqis (2pq(pq − 2p + 2q), 1)-absolutely summing if 1 ⩽ p ⩽ q ⩽ 2 and (p, 1)-absolutely summing if 1 ⩽ p ⩽ 2 ⩽ q ⩽ ∞ or 2 ⩽ p ⩽ q ⩽ ∞. As a corollary, it follows that a (p, 1)-absolutely summing operator, p > 1, need not have the Dunford-Pettis property; this observation answering a question ...
openaire   +2 more sources

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang   +9 more
wiley   +1 more source

MAGELLAN: Metacognitive predictions of learning progress guide autotelic LLM agents in large goal spaces [PDF]

open access: yesarXiv
Open-ended learning agents must efficiently prioritize goals in vast possibility spaces, focusing on those that maximize learning progress (LP). When such autotelic exploration is achieved by LLM agents trained with online RL in high-dimensional and evolving goal spaces, a key challenge for LP prediction is modeling one's own competence, a form of ...
arxiv  

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara   +7 more
wiley   +1 more source

On the Approximability of the Yolk in the Spatial Model of Voting [PDF]

open access: yesarXiv
In the spatial model of voting, the yolk and LP (linear programming) yolk are important solution concepts for predicting outcomes for a committee of voters. McKelvey and Tovey showed that the LP yolk provides a lower bound approximation for the size of the yolk and there has been considerable debate on whether the LP yolk is a good approximation of the
arxiv  

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

open access: yesAdvanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie   +5 more
wiley   +1 more source

Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi   +7 more
wiley   +1 more source

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