Results 31 to 40 of about 298 (140)

Impact of surgery and complications on GI recovery after SBO: Insights from the SnapSBO cohort

open access: yesColorectal Disease, Volume 28, Issue 3, March 2026.
Abstract Background Small bowel obstruction (SBO) is a common surgical emergency associated with impaired gastrointestinal (GI) function and prolonged recovery. The PRO‐diGI patient‐reported outcome measure (PROM) assesses patients' reports on key domains of appetite, nausea, bowel function, well‐being and overall GI function.
Matthew J. Lee   +321 more
wiley   +1 more source

SKALE: An Interpretable Multiscale Machine Learning Model for Decoding Phase‐Specific Protein Aggregation in Neurodegenerative Proteinopathies

open access: yesAggregate, Volume 7, Issue 2, February 2026.
Protein aggregation drives diverse degenerative diseases, yet its molecular origins are difficult to predict. SKALE uses interpretable machine learning to link sequence, structure, and dynamics, revealing how local structural weakening triggers aggregation.
Wei Xuan Wilson Loo   +7 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu   +5 more
wiley   +1 more source

Weak Physics‐Guided Multi‐Agent Learning for Surface to Subsurface Moisture Estimation Across Diverse Climate and Soil Conditions

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 1, February 2026.
Abstract Estimating subsurface soil moisture remains challenging due to limited in situ observations and the complexity of soil water dynamics. Although surface soil moisture can be retrieved from satellites with high accuracy, deeper layers are not directly observable. Traditional physics‐based models that predict subsurface soil moisture require site‐
Abhilash Singh   +2 more
wiley   +1 more source

Detecting and Modeling Emotional Landscapes Through Deep Learning, GPT‐4.1, and 3D Spatial Interpolation

open access: yesTransactions in GIS, Volume 30, Issue 1, February 2026.
ABSTRACT This research provides new directions in conceptualizing emotional geographies at the landscape level using a combination of textual deep learning (DL) and GPT‐based spatial emotion detection and interpolation using 3D empirical Bayesian kriging.
Christopher J. Anderson
wiley   +1 more source

Phospholipid Interconversion and Transport Are Altered in Glaucoma

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards   +5 more
wiley   +1 more source

Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang   +32 more
wiley   +1 more source

Threshold Effects of Maternal Vitamin C in Late Pregnancy on Infant Social Competence: A Nonlinear Dose‐Response Analysis in a Birth Cohort

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
This prospective cohort study analysing 442 mother‐offspring pairs reveals a nonlinear dose‐response relationship between late‐pregnancy serum vitamin C concentration and early offspring social competence. The strongest association was observed at low concentrations (≤ 4.9 μmol/L, β = 0.654/μmol), with diminishing effects at moderate levels (4.9–49 ...
Cui Li, Ji Jiafen, Ni Juan, Li Rui xiang
wiley   +1 more source

When Protein Structure Embedding Meets Large Language Models. [PDF]

open access: yesGenes (Basel), 2023
Ali S, Chourasia P, Patterson M.
europepmc   +1 more source

An empirical evaluation of Lex/Yacc and ANTLR parser generation tools. [PDF]

open access: yesPLoS One, 2022
Ortin F   +3 more
europepmc   +1 more source

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