Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing
Advanced Science, EarlyView.A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo +11 more
wiley +1 more source
RURAL INFRASTRUCTURE, TRANSACTIONS COSTS, AND MARKETED SURPLUS IN KENYA
We develop a conceptual framework for quantifying fixed transactions costs facing semisubsistence households. Using household survey data from a sample of 324 Kenyan maize farmers, we generate estimates of household supply and demand schedules, as well ...
Karanja, Daniel David +2 more
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Evaluating the impact of assisted natural regeneration and afforestation on soil erosion dynamics using high-resolution imagery in semi-arid Ethiopia. [PDF]
Sci RepSisay MW.
europepmc +1 more source
Advanced Science, EarlyView.This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun +14 more
wiley +1 more source
Adoption and expansion of robotic surgery across General Surgery in the United Kingdom: a 10-year procedure-specific analysis (2015-2024). [PDF]
J Robot SurgDonald N, Sebastian J, Preziosi G.
europepmc +1 more source
Advanced Electronic Materials, EarlyView.Our work bridges the gap between skyrmion discovery and material design by demonstrating how atomic‐scale control of exchange interactions enables tunable skyrmion phase transitions in centrosymmetric magnetic metals. ABSTRACT Magnetic skyrmions are topologically protected spin states that hold promise for shaping the future of electronics.
Dasuni N. Rathnaweera +9 more
wiley +1 more source
Exploring the influence of nanosilica on monoterpene biosynthesis, PAL1 and LS gene expression in cumin (Cuminum cyminum L.) under water-deficit stress. [PDF]
BMC Plant BiolAmeri Bafqi ME +3 more
europepmc +1 more source
Ionic Elastomer Interface for Low‐Pressure and Durable All‐Solid‐State Batteries
Advanced Energy Materials, EarlyView.This work reports an ionically conductive elastomer that enables stable all‐solid‐state batteries（ASSBs）under low external pressure. The soft elastomeric matrix, integrated with a LiG3‐based conductive phase(lithium bis(trifluoromethanesulfonyl)imide and triethylene glycol dimethyl ether), simultaneously delivers high ionic conductivity and mechanical ...
Jiaxu Zhang +15 more
wiley +1 more source
Distinct regional allergen sensitization patterns in pediatric populations: A comparative latent class analysis of multiple antigen simultaneous test-derived sensitization profiles in Japan and Taiwan. [PDF]
Asia Pac AllergyLin CW +11 more
europepmc +1 more source
Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries
Advanced Energy Materials, EarlyView.This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang +6 more
wiley +1 more source