Results 191 to 200 of about 131,427 (295)

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

open access: yesBrain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen   +8 more
wiley   +1 more source

Acute and post-acute neurobehavioral responses to lysergic acid diethylamide in healthy subjects: a randomized controlled study. [PDF]

open access: yesNeuropsychopharmacology
Calder AE   +9 more
europepmc   +1 more source

INHBB Promotes Colorectal Cancer Progression by Inducing CD8+ T Cell Exhaustion via the ACVR2B‐SMAD Signaling Axis

open access: yesCancer Science, EarlyView.
INHBB secreted by colorectal cancer cells activates ACVR2B‐SMAD signaling to induce CD8+ T‐cell exhaustion and drive tumor progression. SB431542 blocks this oncogenic immune‐suppressive axis. ABSTRACT To investigate the expression pattern, biological functions and regulatory mechanisms of inhibin beta B (INHBB) in colorectal cancer (CRC), and to ...
Guanghui Liu   +5 more
wiley   +1 more source

Looking at a Blind Spot: Using a Longitudinal Population Cohort Study to Examine Inequalities in Child Social Worker Contact Among Mothers Experiencing Domestic Abuse in Scotland

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Research on inequalities in children's services in the UK highlights a lack of systematic data on parental demographics, obstructing analysis of structural factors influencing children's outcomes. Using Growing Up in Scotland, a nationally representative longitudinal child cohort study of children born in 2004–2005, we investigate social ...
Valeria Skafida   +2 more
wiley   +1 more source

Layer3D: A 3D Layered Representation for Multiview Vector Graphics

open access: yesComputer Graphics Forum, EarlyView.
Abstract We present Layer3D, a novel 3D neural representation that models objects as collections of decomposable neural implicit primitives. These primitives enable the generation of layered images with consistent correspondences across viewpoints, establishing a flexible framework for multiview vector graphics decomposition.
Zhongyue Guan, Yixin Hu, Zeyu Wang
wiley   +1 more source

How the Army, CIA Dabbled in LSD

open access: yes, 1975
Egan, Richard
core  

Clinical Outcomes of Fixed Dental Prostheses Supported by Teeth or Implants in the Posterior Region—A Long‐Term Retrospective Multicenter Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Background Few long‐term studies compare tooth‐ and implant‐supported fixed dental prostheses (FDPs) in the posterior region. Objectives To compare the 5‐ and 10‐year survival and complication outcomes of tooth‐ and implant‐supported FDPs and to assess patient‐reported effects. Material and Methods This retrospective multicenter clinical study
Zahra Athab Abduljabbar   +5 more
wiley   +1 more source

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