Results 171 to 180 of about 50,280 (279)

The Journey Towards Withdrawal: Nurses' Experiences of End-of-Life Decisions in Cardiothoracic Intensive Care. [PDF]

Nurs Res Pract
Björklund Pal C, Sjögren Forss K.
europepmc   +1 more source

Association of HRD Score With Efficacy of Neoadjuvant Short‐Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Homologous recombination deficiency (HRD) has been reported to be associated with increased sensitivity to platinum‐based treatment and radiotherapy in some solid tumors. Aim This study investigated the correlation between HRD score and treatment response to neoadjuvant short‐course radiotherapy combined with sequential chemotherapy
Xin Ran, He Xiao, Peng Zhou, Juan He, Mengyuan Si, Xiuqiong Chen, Xiaona Su, Zhuo Chen, Jia Du, Xiaoyan Dai, Xiao Yang, Haode Shen, Zongsheng He, Fan Li, Mengxia Li, Chuan Chen   +15 more
wiley   +1 more source

Salinity gradients shape rhizosphere bacterial diversity and assembly of wheat in saline-alkali rice-wheat rotation soils. [PDF]

Front Microbiol
Li J, Zhang Y, Liu Q, Jiang F, Liu X, Xu J, Liu P, Wang Y, Wu C, Zhao S.   +9 more
europepmc   +1 more source

MEK inhibition achieves robust and durable responses in Erdheim–Chester disease

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract Erdheim–Chester disease (ECD) is a rare histiocytic neoplasm characterized by heterogeneous clinical manifestations and limited evidence to guide targeted therapy. While MEK inhibitors (MEKi) are increasingly used, data on their real‐world efficacy, durability, and safety remain incomplete.
Francesco Pegoraro, Félicien Triboulet, Matthias Papo, Francesco Peyronel, Anita Argentieri, Jerome Razanamahery, Ahmed Idbaih, Polyzois Makras, Ofer Shpilberg, Oshrat Hershkovitz‐Rokah, Michael Girschikofsky, Matthew Collin, Kristian Bowles, Satyen H. Gohil, Rodothea Amerikanou, Emmanuel Ledoult, Tanguy Le Scornet, Mathilde de Menthon, Etienne Riviere, Xavier Boulu, Henry Dupuy, Achille Aouba, Stanislas Faguer, Xavier Solanich, Elena Sieni, Stéphane Barete, Chiara Bellino, Alessandro Tomelleri, Corrado Campochiaro, Lorenzo Dagna, Zahir Amoura, Jean‐François Emile, Fleur Cohen‐Aubart, Augusto Vaglio, Julien Haroche   +34 more
wiley   +1 more source

Beyond implementation: what drives long-term sustainment of life-sustaining treatment documentation in VA home based primary care. [PDF]

BMC Health Serv Res
Kononowech J, Magid KH, Haverhals LM, Beltran J, Levy CR.   +4 more
europepmc   +1 more source

Analyzing the spatiotemporal dynamics of land use land cover change and its effects on land surface temperature in Weyib watershed, South Eastern Ethiopia. [PDF]

Sci Rep
Dararo KF, Tiye FS, Geleto DL.
europepmc   +1 more source

Cooccurrence of Homologous Recombination Deficiency and Mismatch Repair Deficiency in Colorectal Cancer

MedComm, Volume 7, Issue 10, October 2026.
Cooccurrence of dMMR and HRD in colorectal cancer. On the left blue shaded area, the dMMR (deficient mismatch repair) pathway is shown as a result of the loss of key DNA repair genes MLH1, MSH2, MSH6, and PMS2, which cause single strand breaks.
Xu Zhang, Hao Xu, Kailai Wang, Wangxiong Hu   +3 more
wiley   +1 more source

Nonlinear and inequality-related heterogeneity in green cooling across Chinese urban agglomerations: a SHAP-based random forest analysis. [PDF]

Front Public Health
Zhang Z, Yang Z, Ouyang L.
europepmc   +1 more source

Factors Associated With Family Caregivers' Attitudes Toward Withholding Life‐Sustaining Treatment in Older Adults With Dementia: A Cross‐Sectional Study

Nursing Open, Volume 13, Issue 10, October 2026.
ABSTRACT Aim To examine factors associated with family caregivers' attitudes toward withholding life‐sustaining treatments (LSTs) for older adults with dementia. Design Cross‐sectional study. Methods A questionnaire survey assessed advance care planning (ACP) knowledge, perceptions of a good death, caregiver burden, and attitudes toward withholding ...
Kukjin Kim, Yoonah Noh, Jia Lee
wiley   +1 more source

Reducing sitting time is essential for preserving sarcopenia and functional independence with aging: a comparative cross-sectional study. [PDF]

PeerJ
Yoon TH, Jee YS.
europepmc   +1 more source