Novel Long-Read Sequencing Method for Characterisation of Hepatitis B Transcripts Show High Expression of Chimeric HBV/Human RNA. [PDF]
Liver IntABSTRACT Background Hepatitis B virus (HBV) genomes integrated into human DNA significantly contribute to surface antigen (HBsAg) production and may drive hepatocellular carcinoma (HCC). Long‐read sequencing methods like Nanopore offer advantages over short‐read next‐generation sequencing (NGS) by providing continuous reads of whole transcripts, but ...
Stenbäck JB +6 more
europepmc +2 more sources
gammaSTAR: A framework for the development of dynamic, real-time capable MR sequences. [PDF]
Magn Reson MedAbstract Purpose To present the real‐time capability and advanced MR sequence library of the MR sequence development framework gammaSTAR. Methods The presented platform consists of four different components: (1) a frontend for sequence development combined with a Python backend for sequence generation; (2) a Lua backend for the creation of hardware ...
Konstandin S, Günther M, Hoinkiss DC.
europepmc +2 more sources
PBPK-Led Assessment of Antimalarial Drug Concentrations in Breastmilk: A Strategy for Optimal Use of Prediction Methods to Guide Decision Making in an Understudied Population. [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT Treatment of breastfeeding mothers with malaria is challenging due to the lack of information describing drug exposure in milk and the daily dose to the breastfed infant. Physiologically based pharmacokinetic (PBPK) modeling was used to predict milk‐to‐plasma (M/P) ratios, infant daily doses (IDD) and relative infant doses (RID) for five ...
Almond LM +11 more
europepmc +2 more sources
What Do They Think? The Opinions of Women With Intellectual Disabilities on Affective-Sexual Relationships: An Interview-Based Study. [PDF]
J Appl Res Intellect DisabilABSTRACT Background Although the rights to sexuality and intimacy are increasingly recognised, it is a widely held assumption that women with intellectual disabilities are unable to express their sexuality freely, partly due to a lack of research and information on the topic. Objective To explore the perspectives of women with intellectual disabilities
Beltran-Arreche M +2 more
europepmc +2 more sources
BrainFusion: a Low-Code, Reproducible, and Deployable Software Framework for Multimodal Brain‒Computer Interface and Brain‒Body Interaction Research. [PDF]
Adv Sci (Weinh)BrainFusion is a low‐code software framework for multimodal brain–computer interface (BCI) and brain–body interaction research. It supports electroencephalography (EEG), functional near‐infrared spectroscopy (fNIRS), electromyography (EMG), and electrocardiography (ECG) integration with standardized preprocessing, feature fusion, and model ...
Li W +10 more
europepmc +2 more sources
Molecular Classification of Endometrial Cancers Using an Integrative DNA Sequencing Panel. [PDF]
J Surg OncolABSTRACT Background and Objectives Adoption of molecular classification in endometrial cancer (EC) into clinical practice remains challenging due to complexity in coordination of multiple assays. We aimed to develop a simple molecular technique to classify ECs into four subgroups using our custom‐designed targeted sequencing panel.
Kim SR +13 more
europepmc +2 more sources
The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis [PDF]
, 2020 Purpose: Aberrant expression of microRNAs (miRNAs) has been discovered in prostate cancer progression however their function is not well understood, thereby further investigation is required to understand the importance of underlying mechanisms and their
Arisan, E.D. +9 more
core +1 more source
A Classification of Scripting Systems for Entertainment and Serious Computer Games [PDF]
, 2011 The technology base for modern computer games is usually provided by a game engine. Many game engines have built-in dedicated scripting languages that allow the development of complete games that are built using those engines, as well as extensive ...
Anderson, Eike F.
core +1 more source
Electrical engineering & Electromechanics, 2016 The theoretical bases of calculation of electromagnetic quantities and time-phase relationship are presented for the turbo-generators. This is done by numerical calculations of the magnetic field in the software environment package FEMM (Finite Element ...
V.I. Milykh, N.V. Polyakova
doaj +1 more source
Critters in the Classroom: A 3D Computer-Game-Like Tool for Teaching Programming to Computer Animation Students [PDF]
, 2007 The brewing crisis threatening computer science education is a well documented fact. To counter this and to increase enrolment and retention in computer science related degrees, it has been suggested to make programming "more fun" and to offer ...
Anderson, Eike F., McLoughlin, L.
core +1 more source