Results 131 to 140 of about 3,483 (260)

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

Animal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li, Yanming Chen, Xinyi Xiao, Guoheng Xu   +3 more
wiley   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Application of a neural network model in estimation of frictional features of tribofilms derived from multiple lubricant additives. [PDF]

Sci Rep
Noma H, Aoki S, Kobayashi K.
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Analytical Studies on the Functional Effect of Sulfur-Containing Extreme Pressure Additives

Chemical Engineering Transactions
Proper maintenance of machine components exposed to high pressure and temperature is essential for efficient and safe operation. One of the most important additives in these lubricants is the extreme pressure (EP) additive, which allows lubricants to ...
Roland Nagy, Gábor Nagy
doaj  

Alkali‐Catalyzed Synthesis of Acylglycerol Estolides Exclusively from Castor Oil

Journal of the American Oil Chemists' Society, EarlyView.
This work advances sustainable chemistry by converting renewable castor oil into high‐performance estolides via solvent‐free, low‐energy catalysis. ABSTRACT Estolides are oligomers composed of fatty acid (FA) monomers linked through secondary ester bonds located along the mid‐chain region.
Lucas Natã de Melo, Simoni Margareti Plentz Meneghetti, Mario Roberto Meneghetti, Janaína Heberle Bortoluzzi   +3 more
wiley   +1 more source

Radiative Hybrid Nanofluid Flow Over a Porous Riga Surface: A Fuzzy–ANN Modeling Approach

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a fuzzy–ANN model to investigate the nonlinear thermal transport in a tangent hyperbolic (Tanh) hybrid nanofluid flow past a porous Riga surface, considering the effects of Rosseland diffusion, chemical reactions, and internal volumetric heating.
Azad Hussain, Rabia Zetoon, Reeha Iqbal
wiley   +1 more source

Numerical Study of MHD Hybrid Nanofluid Flow With Multiple Slip Effects Over a Variable Porous Stretching Surface

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This work discusses the thermal performance of magnetized hybrid nanofluid flow over a variable porous stretchable surface, emphasizing the underlying physical mechanisms governing heat and mass transfer. The Cattaneo–Christov flux model is used in place of Fourier's and Fick's laws to incorporate relaxation effects, ensuring a more realistic ...
Mounirah Areshi, Abdul Bariq, Salemah A. Almutlak, Fahad Maqbul Alamrani, Zehba Raizah, Anwar Saeed   +5 more
wiley   +1 more source

Bioconvective Unsteady Casson Hybrid Nanofluid Flow on a Variable Darcy Regime Between Two Rotating Disks With Variable Heat Source

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study carries significant consequences in various engineering applications, such as cooling rotating disk surfaces, improving chemical reactor performance, and designing filtration systems. Considering these main applications in view, the aim of this study is to investigate time‐dependent Casson hybrid nanofluid flow on a permeable ...
Ebrahem A. Algehyne, Abdul Bariq, Mounirah Areshi, Fahad Maqbul Alamrani, Zehba Raizah, Izharul Haq, Anwar Saeed   +6 more
wiley   +1 more source