Results 161 to 170 of about 803,930 (187)
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Novel hydroxypropyl-guar gellable lubricant eye drops for treatment of dry eye
Advances in Therapy, 2010OBJECTIVE|: The objective of this review is to evaluate the safety and efficacy of polyethylene glycol 400/propylene glycol/hydroxypropyl-guar (Systane® Ultra [PEG/PG with HP-guar], Alcon Laboratories, Inc., Fort Worth, TX, USA) lubricant eye drops in reducing the signs and symptoms of dry-eye disease. METHODS|: A systematic literature search utilizing
exaly +3 more sources
Evaluation of the Preserving Efficacy of Lubricant Eye Drops with a Novel Preservative System
Journal of Ocular Pharmacology and Therapeutics, 2006Products provided in multidose containers must be adequately preserved in order to prevent contamination during repeated use. The aim of this study was to evaluate the ability of a lubricant eye drop formulation without traditional preservatives to control and prevent contamination under extreme microbial conditions. Bottles of a new lubricant eye drop
Barry A Schlech
exaly +3 more sources
Corneal staining reductions observed after treatment with Systane® Lubricant Eye Drops
Advances in Therapy, 2008Because of the added emphasis on ocular surface damage included in the Dry Eye Workshop's revised definition of dry eye, an evaluation of corneal staining reductions was conducted for propylene glycol/polyethylene glycol 400-based artificial tear drops (Systane Lubricant Eye Drops; Alcon Laboratories, Fort Worth, TX, USA).An analysis was conducted on ...
Mike T Christensen
exaly +3 more sources
Efficacy in Patients with Dry Eye After Treatment with a New Lubricant Eye Drop Formulation
Journal of Ocular Pharmacology and Therapeutics, 2010Abstract Purpose: The effective management of dry eye must include a clinically meaningful reduction in ocular staining. Evaluations of corneal and conjunctival staining and other ocular symptoms of dry eye were conducted for a new formulation of polyethylene glycol 400/propylene glycol-based ...
William F, Davitt +3 more
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Experimental and Toxicologic Pathology, 2017
Ingredients of lubricant eye drops are potentially harmful to the ocular surface. The products Optive, Optive Fusion, Neopt were tested regarding corneal irritability versus Vismed Multi and 0.01% benzalkonium chloride as negative and positive control, respectively. Formulas (30-40μl per hour) were applied hourly in-vitro for six days on rabbit corneas
Norbert Schrage
exaly +3 more sources
Ingredients of lubricant eye drops are potentially harmful to the ocular surface. The products Optive, Optive Fusion, Neopt were tested regarding corneal irritability versus Vismed Multi and 0.01% benzalkonium chloride as negative and positive control, respectively. Formulas (30-40μl per hour) were applied hourly in-vitro for six days on rabbit corneas
Norbert Schrage
exaly +3 more sources
Systane® Ultra Lubricant Eye Drops for Treatment of Contact Lens–Related Dryness
Eye and Contact Lens, 2014To assess the clinical performance of Systane Ultra lubricant eye drops in daily disposable soft contact lens wearers who experience contact lens-related dryness.In this randomized, investigator-masked study, daily disposable lens wearers with symptoms of dryness were randomized to use Systane Ultra lubricant eye drops or to no treatment. The lubricant
Christopher W Lievens, Jami R Kern
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Clinical Efficacy of an Oil‐based Lubricant Eye Drop in Dry Eye Patients with Lipid Deficiency
Acta Ophthalmologica, 2015PurposeTo demonstrate the superior efficacy of a propylene glycol‐based, micro‐emulsion eye drop (SYSB; Systane® Balance) over Preservative‐Free 0.9% Saline (PFS) Solution in patients with lipid‐deficient dry eye.MethodsThis was a multicenter, observer masked, parallel‐design study (powered to show superiority). Subjects were randomized to receive SYSB
M. Labetoulle +8 more
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Contact Lens and Anterior Eye, 2019
To investigate the effect of the addition of electrolytes, basic tear solution (BTS), and sodium carboxymethylcellulose (SCMS) on the tear ferning (TF) patterns of Blink Contact Soothing Eye Drops® and Refresh Plus Tears®.Samples of Blink Contact Soothing Eye Drops® and Refresh Plus Tears® (10 μL) were mixed with different volumes (3-30 μL) of several ...
openaire +2 more sources
To investigate the effect of the addition of electrolytes, basic tear solution (BTS), and sodium carboxymethylcellulose (SCMS) on the tear ferning (TF) patterns of Blink Contact Soothing Eye Drops® and Refresh Plus Tears®.Samples of Blink Contact Soothing Eye Drops® and Refresh Plus Tears® (10 μL) were mixed with different volumes (3-30 μL) of several ...
openaire +2 more sources
Ophthalmologica, 2009
<i>Purpose:</i> To evaluate the effects of a mid-viscosity mucomimetic lubricant eye drop containing hydroxypropyl guar (HPG) as a gelling agent on computerized perimetry FASTPAC test results of primary open-angle glaucoma (POAG) patients with trachomatous dry eye. <i>Methods:</i> Both eyes of 33 patients with bilateral POAG and
Mustafa, Guzey +4 more
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<i>Purpose:</i> To evaluate the effects of a mid-viscosity mucomimetic lubricant eye drop containing hydroxypropyl guar (HPG) as a gelling agent on computerized perimetry FASTPAC test results of primary open-angle glaucoma (POAG) patients with trachomatous dry eye. <i>Methods:</i> Both eyes of 33 patients with bilateral POAG and
Mustafa, Guzey +4 more
openaire +2 more sources
Acta Ophthalmologica, 2015
PurposeThe objective of this study was to compare the efficacy and safety of a polyethylene glycol/propylene glycol based eye drop (PEG/PG; Systane® Ultra) to an osmoprotective‐carboxymethylcellulose based eye drop (CMC/O; Optive®) in patients with dry eye.MethodsThis was a multicenter, observer masked, parallel‐design study, subjects were randomized ...
M. Labetoulle +4 more
openaire +1 more source
PurposeThe objective of this study was to compare the efficacy and safety of a polyethylene glycol/propylene glycol based eye drop (PEG/PG; Systane® Ultra) to an osmoprotective‐carboxymethylcellulose based eye drop (CMC/O; Optive®) in patients with dry eye.MethodsThis was a multicenter, observer masked, parallel‐design study, subjects were randomized ...
M. Labetoulle +4 more
openaire +1 more source