Results 181 to 190 of about 242,259 (303)

Developing FGF2 Mutants with Selectively Reduced Heparan Sulfate Affinity to Explore Their Impact on FGFR1 Signaling

open access: yesChemBioChem, Accepted Article.
Fibroblast growth factor 2 (FGF2) regulates signal transduction by forming complexes with its receptors, FGF receptors (FGFRs), and heparan sulfate (HS), playing a crucial role in biological systems. Although HS has been suggested to modulate FGF/FGFR signaling as a co‐receptor, multiple hypotheses exist regarding how HS affects FGF/FGFR signaling, and
Yuga Okada   +5 more
wiley   +1 more source

Technical development and In Silico implementation of SyntheticMR in head and neck adaptive radiation therapy: A prospective R-IDEAL stage 0/1 technology development report. [PDF]

open access: yesJ Appl Clin Med Phys
McCullum L   +13 more
europepmc   +1 more source

Light‐Triggered Disassembly of Peptide Nanostructures

open access: yesChemBioChem, EarlyView.
Two amphiphilic peptides incorporating anthracene as a light‐responsive moiety that assemble into 2D‐sheets or ribbons are designed. These nanostructures are disassembled upon irradiation with 365 nm light by bimolecular [4 + 4] cycloaddition. The reaction kinetics are depended on peptide preorganization, linking structure to reactivity.
Raphael Meyer   +6 more
wiley   +1 more source

Readdressing rapid sequence induction and intubation using ketamine or etomidate: A systematic review and meta-analysis of randomized clinical trials. [PDF]

open access: yesMedicine (Baltimore)
de Morais LB   +5 more
europepmc   +1 more source

Reproducibility in Artificial Photosynthesis: A Case Study on SnO₂/Cu Photocatalysts

open access: yesChemCatChem, EarlyView.
Sketch representing that the remaining sol gel adsorbate (ethanol) showed pronounced effects on catalytic evaluation under controlled environment and offered electrons for the reprecipitation of leached copper. Abstract This study examines how synthesis routes and storage conditions affect the reliability of photocatalytic data for SnO₂/Cu catalysts ...
Gustavo D. Iga   +4 more
wiley   +1 more source

Tislelizumab: Structural Innovations and Expanding Clinical Horizons in Next‐Generation PD‐1 Immunotherapy

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The interaction of tislelizumab with PD‐1/PD‐L1 in the tumor microenvironment. Tislelizumab targets PD‐1 on T cells, blocking its interaction with PD‐L1 on tumor cells. This action is facilitated by a modified F(ab) region that limits Fc‐γ receptor binding, thereby enhancing the antitumor immune response. ABSTRACT Tislelizumab is a next‐generation PD‐1
Thy T. Nguyen   +4 more
wiley   +1 more source

Portal bile acid composition and microbiota along the <i>murine</i> intestinal tract exhibit sex differences in physiology. [PDF]

open access: yesGut Microbes
Reichardt F   +6 more
europepmc   +1 more source

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