Results 71 to 80 of about 254,556 (238)
Arthritis &Rheumatology, Accepted Article.Background The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasing immunosuppressive (IST) and anti‐fibrotic therapies available. However, their real‐world use remains unclear. Objectives To analyze treatment trends and the effect of IST and anti‐fibrotic therapies on ILD progression ...
Corrado Campochiaro +17 more
wiley +1 more source
A coalition formation value for games with externalities [PDF]
The coalition formation problem in an economy with externalities can be adequately modeled by using games in partition function form (PFF games), proposed by Thrall and Lucas.
Michel Grabisch, Yukihiko Funaki
core
Arthritis &Rheumatology, Accepted Article.Background Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients don't respond. Low inosine‐triphosphate‐pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated ITPA role and the underlying mechanisms in vitro.
Sofia Sindici Forgiarini +19 more
wiley +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract This systematic review examines strategies for docosahexaenoic acid (DHA) production by thraustochytrids, focusing on cultivation techniques, fermentation technologies, and carbon/nitrogen optimization to increase productivity. Among 169 eligible articles, the 100 most productive studies (0.7–10.3 g DHA L−1 per day) were analyzed. Quantitative
Jhiovana Cristielly Carrera Silva da Costa +6 more
wiley +1 more source
Values of Lucas Sequences Modulo Primes
Rocky Mountain Journal of Mathematics, 2003 Let \(F_n\) denote the Fibonacci numbers. It is very easy to show that primes \(p \neq 5\) divide \(F_{p \pm 1}\), but finding the correct sign involves a piece of quadratic reciprocity. \textit{M. Ward} [Pac. J. Math. 11, 379--386 (1961; Zbl 0112.26904)] has observed that the question which primes divide \(F_{(p \pm 1)/k}\) for \(k = 2, 3, 4 \ldots ...
openaire +3 more sources
British Educational Research Journal, EarlyView.Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany +3 more
wiley +1 more source
Form flows function: Learner‐centered game Re‐design in a STEM classroom
British Educational Research Journal, EarlyView.Abstract Re‐designing games facilitates interest‐driven learning and immerses learners in systems thinking. However, there are limited studies exploring how the form and function of tabletop games influence learners' design decisions and learning experiences. To address this gap, we conducted a mixed‐methods study in a STEM classroom in western Canada.
Farzan Baradaran Rahimi +2 more
wiley +1 more source
A Guide to Bayesian Optimization in Bioprocess Engineering
Biotechnology and Bioengineering, EarlyView.ABSTRACT Bayesian optimization has become widely popular across various experimental sciences due to its favorable attributes: it can handle noisy data, perform well with relatively small data sets, and provide adaptive suggestions for sequential experimentation.
Maximilian Siska +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai +9 more
wiley +1 more source