Results 101 to 110 of about 62,692 (304)

Beware the ‘luck’ capstone

open access: yesBritish Journal of Sports Medicine, 2017
The recent BJSM educational review describing an ‘injury prevention pyramid for elite sports teams’, which has been widely promoted through social media, suggests that bad ‘luck’ plays a definitive role in injury occurrence, depicting its notable role as the capstone.1 This is in direct contrast to the rich theoretical and empirical history of injury ...
Sheree Bekker   +3 more
openaire   +3 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Towards a Motivation-Based Approach for Evaluating Goals [PDF]

open access: yes, 2003
Traditional goal-oriented approaches to building intelligent agents only consider absolute satisfaction of goals. However, in continuous domains there may be many instances in which a goal state can only be partially satisfied.
Luck, Michael   +5 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Demotivating Semi-Compatibilism

open access: yesIdeas y Valores, 2009
In this paper, I explore some of the motivations behind John Martin Fischer's semi-compatibilism. Particularly, I look at three reasons Fischer gives for preferring semi-compatibilism to libertarianism. I argue that the first two of these motivations are
Kevin Timpe
doaj  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Should Kane Abandon the Symmetry of Efforts of Will [PDF]

open access: yesPizhūhish/hā-yi Falsafī- Kalāmī
An agent’s efforts of will have long been at the centre of Robert Kane’s influential account of libertarian free will. For several decades it has been a crucial part of his theory that there is a symmetry to these efforts.
Neil Campbell
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Equality of opportunity and luck: Denitions and testable conditions, with an application to income in France [PDF]

open access: yes
We oer a model of equality of opportunity that encompasses dierent conceptions expressed in the public and philosophical debates. In addition to circumstances whose eect on outcome should be compensated and eort which represents a legitimate source of ...
Arnaud LEFRANC, Nicolas PISTOLESI, Alain TRANNOY
core  

Wages, Talents, and Egalitarianism

open access: yesErasmus Journal for Philosophy and Economics, 2018
This paper compares Joseph Heath’s critique of the just deserts rationale for markets with an earlier critique due to Frank Knight, Milton Friedman, and Friedrich Hayek.
Andrew Lister
doaj   +1 more source

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