Results 141 to 150 of about 613,108 (397)

Good Night, and Good Luck: Perspectives on Luck in Management Scholarship

open access: yes, 2016
It is not insignificant that seminal contributions to management scholarship have highlighted luck as an alternative explanation for performance differences between individuals and organizations. Yet it has rarely taken center-stage in scholarship.
Chengwei Liu, Mark de Rond
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Statistics of the occupation time of renewal processes [PDF]

open access: yesJournal of Statistical Physics 104 (2001), 489-524., 2000
We present a systematic study of the statistics of the occupation time and related random variables for stochastic processes with independent intervals of time. According to the nature of the distribution of time intervals, the probability density functions of these random variables have very different scalings in time.
arxiv  

Against the Character Solution to the Problem of Moral Luck [PDF]

open access: yes, 2020
One way to frame the problem of moral luck is as a contradiction in our ordinary ideas about moral responsibility. In the case of two identical reckless drivers where one kills a pedestrian and the other does not, we tend to intuit that they are and are ...
Hartman, Robert J.
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Czym jest szczęście? Analiza zagadnienia na podstawie koncepcji Władysława Tatarkiewicza [What is Happiness? The Analysis on the Basis of Tatarkiewicz’ Conception] [PDF]

open access: yesAnaliza i Egzystencja, 2013
The aim of this article is the analysis of the term of the happiness on the basis of theWładysław Tatarkiewicz’s conception. According to his workO szczęściu (AboutHappiness) happiness is defined here as justified, full, constant satisfaction fromthe ...
Jarosław Dalke   +4 more
doaj  

Legal Luck [PDF]

open access: yes
Explaining the notion of legal luck and exploring its justification. Focusing on how legal luck relates to moral luck, legal causation and negligence, and to civil and criminal ...
Herstein, Ori
core  

Inclusive design and making in practice: Bringing bodily experience into closer contact with making

open access: yes, 2018
This paper develops our understanding of the nature of inclusive design, first through critique of controversies that to some degree downplay inclusive design as a distinct design movement.
Luck, Rachael
core   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

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