Results 41 to 50 of about 949 (162)

Low serum neurofilament light chain values identify optimal responders to dimethyl fumarate in multiple sclerosis treatment

Scientific Reports, 2021
Serum neurofilament light chains (sNfL) are biomarkers of disease activity in multiple sclerosis (MS), but their value to predict response to treatment, and their association with patient immunological profile, need to be further explored.
Paulette Esperanza Walo-Delgado, Susana Sainz de la Maza, Noelia Villarrubia, Enric Monreal, Silvia Medina, Mercedes Espiño, José Ignacio Fernández-Velasco, Eulalia Rodríguez-Martín, Ernesto Roldán, Daniel Lourido, Alfonso Muriel, Jaime Masjuan-Vallejo, Lucienne Costa-Frossard, Luisa María Villar   +13 more
doaj   +1 more source

COVID-19 Associated Pulmonary Aspergillosis (CAPA): Hospital or Home Environment as a Source of Life-Threatening Aspergillus fumigatus Infection?

Journal of Fungi, 2022
Most cases of invasive aspergillosis are caused by Aspergillus fumigatus, whose conidia are ubiquitous in the environment. Additionally, in indoor environments, such as houses or hospitals, conidia are frequently detected too.
Teresa Peláez-García de la Rasilla, Irene González-Jiménez, Andrea Fernández-Arroyo, Alejandra Roldán, Jose Luis Carretero-Ares, Marta García-Clemente, Mauricio Telenti-Asensio, Emilio García-Prieto, Mar Martínez-Suarez, Fernando Vázquez-Valdés, Santiago Melón-García, Luis Caminal-Montero, Inmaculada Fernández-Simón, Emilia Mellado, María Luisa Sánchez-Núñez   +14 more
doaj   +1 more source

Una mirada matemática por Sevilla. El parque María Luisa [PDF]

, 2021
El papel que ha jugado y que juega la Educación en nuestras vidas es fundamental, forma a la sociedad con el fin de generar una colectividad unida, colaborativa, cooperante, inteligente y capacitada.
Jiménez Roldán, María Inmaculada
core  

Novel CYFIP2 Frameshift Variant Linked to Dyskinetic Crises: Functional Studies Show Impaired Cell Motility

Clinical Genetics, Volume 108, Issue 6, Page 708-712, December 2025.
We describe a novel CYFIP2 frameshift variant linked to dyskinetic crises. Functional studies in patient‐derived fibroblasts reveal impaired actin cytoskeleton regulation and reduced cell motility, supporting a pathogenic role for CYFIP2 in movement disorders.
María Eugenia Amato, Marcos Frías, Alfredo Cerisola, Mònica Roldán, Juan Darío Ortigoza‐Escobar   +4 more
wiley   +1 more source

Role of B Cell Profile for Predicting Secondary Autoimmunity in Patients Treated With Alemtuzumab

Frontiers in Immunology, 2021
ObjectiveTo explore if baseline blood lymphocyte profile could identify relapsing remitting multiple sclerosis (RRMS) patients at higher risk of developing secondary autoimmune adverse events (AIAEs) after alemtuzumab treatment.MethodsMulticenter ...
Paulette Esperanza Walo-Delgado, Enric Monreal, Silvia Medina, Ester Quintana, Susana Sainz de la Maza, José Ignacio Fernández-Velasco, Paloma Lapuente, Manuel Comabella, Lluis Ramió-Torrentà, Xavier Montalban, Luciana Midaglia, Noelia Villarrubia, Angela Carrasco-Sayalero, Eulalia Rodríguez-Martín, Ernesto Roldán, José Meca-Lallana, Roberto Alvarez-Lafuente, Jaime Masjuan, Lucienne Costa-Frossard, Luisa Maria Villar   +19 more
doaj   +1 more source

The Apical Localization of Na+, K+-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β2 Subunit

Frontiers in Physiology, 2016
Na+, K+-ATPase, or the Na+ pump, is a key component in the maintenance of the epithelial phenotype. In most epithelia, the pump is located in the basolateral domain.
Jorge Lobato Álvarez, María Luisa Roldán, Teresa del Carmen López Murillo, José Bonilla Delgado, Ricardo González Ramírez, Liora Shoshani   +5 more
doaj   +1 more source

Effects of combined antiretroviral therapy on B- and T-cell release from production sites in long-term treated HIV-1⁺ patients

Journal of Translational Medicine, 2012
Background The immune system reconstitution in HIV-1- infected patients undergoing combined antiretroviral therapy is routinely evaluated by T-cell phenotyping, even though the infection also impairs the B-cell mediated immunity.
Quiros-Roldan Eugenia, Serana Federico, Chiarini Marco, Zanotti Cinzia, Sottini Alessandra, Gotti Daria, Torti Carlo, Caimi Luigi, Imberti Luisa   +8 more
doaj   +1 more source

Imágenes de San José en la estirpe Roldán

Norba. Arte, 2019
La devoción a San José comienza de manera intensa a partir del final de la baja Edad Media. Se analizan en el presente artículo diferentes formas iconográficas de éste, sobre todo la de san José y el niño Jesus itinerante y san José con el niño en sus ...
Jesús Porres Benavides
doaj  

The Impact of Immune System Aging on Infectious Diseases

Microorganisms
Immune system aging is becoming a field of increasing public health interest because of prolonged life expectancy, which is not paralleled by an increase in health expectancy.
Eugenia Quiros-Roldan, Alessandra Sottini, Pier Giorgio Natali, Luisa Imberti   +3 more
doaj   +1 more source

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis

Frontiers in Immunology, 2021
Patients with multiple sclerosis (MS) suffer with age an early immunosenescence process, which influence the treatment response and increase the risk of infections. We explored whether lipid-specific oligoclonal IgM bands (LS-OCMB) associated with highly
Carmen Picón, Carmen Picón, Amalia Tejeda-Velarde, José Ignacio Fernández-Velasco, Manuel Comabella, Roberto Álvarez-Lafuente, Ester Quintana, Susana Sainz de la Maza, Enric Monreal, Noelia Villarrubia, José Carlos Álvarez-Cermeño, María Inmaculada Domínguez-Mozo, Lluís Ramió-Torrentà, Eulalia Rodríguez-Martín, Ernesto Roldán, Yolanda Aladro, Silvia Medina, Mercedes Espiño, Jaime Masjuan, Clara Matute-Blanch, Marta Muñoz-San Martín, Carmen Espejo, Carmen Guaza, Alfonso Muriel, Lucienne Costa-Frossard, Luisa María Villar   +25 more
doaj   +1 more source