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Results 201 to 210 of about 657,884 (297)

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Reducing Inhomogeneous MT (ihMT) Acquisition Time Using Frequency Alternation at Low Duty Cycle for Single Offset (FALSO) MT Preparations

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate Frequency Alternation at Low duty cycle for Single Offset (FALSO) as a novel Magnetization Transfer (MT) preparation scheme to increase speed and/or spatial resolution of inhomogeneous MT (ihMT) MRI by reducing the number of volumes required.
Gopal Varma +5 more
wiley +1 more source

Structure-Function Relationship Between Optic Nerve Head Morphometry and Virtual Reality-Based Perimetry in Open-Angle Glaucoma. [PDF]

Transl Vis Sci Technol
Lüke JN +6 more
europepmc +1 more source

Nerve Ultrasound Detects Peripheral Nerve Enlargement in Cerebrotendinous Xanthomatosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by variants in the CYP27A1 gene, resulting in cholestanol accumulation in various tissues, including peripheral nerves. Polyneuropathy is common but often under‐recognized in CTX.
Antonio Edvan Camelo‐Filho +8 more
wiley +1 more source

Understanding Treatment Care and Delays in Acquired Hemophilia A: A Population-Based Study From Nova Scotia, Canada. [PDF]

EJHaem
Blackman R +4 more
europepmc +1 more source

Computational Evaluation of Statin Analogs Targeting HMG‐CoA Reductase for Coronary Artery Disease Treatment

ChemistryOpen, EarlyView.
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo +4 more
wiley +1 more source

Correction: Leveraging deep learning models to increase the representation of nomadic pastoralists in health campaigns and demographic surveillance. [PDF]

PLOS Glob Public Health
Liu B +11 more
europepmc +1 more source

Exploring biofiber properties and their influence on biocomposite tensile properties

Polymer International, EarlyView.
The study measured the physical, flow and chemical properties of 10 biofibers. It characterized the tensile properties of derived biocomposites and linked them using regression models, showing robust predictive performance. Abstract Biofibers serve as effective reinforcements for neat polylactic acid (PLA) in biocomposites, offering an attractive ...
Oluwafemi A. Oyedeji +5 more
wiley +1 more source

Uganda's endemic flora: discovery, diversity, distribution and threat status. [PDF]

PhytoKeys
Kalema J +13 more
europepmc +1 more source

Dual‐Crosslinked Hydrogels With Enhanced Mechanical and Thermal Properties

Journal of Polymer Science, EarlyView.
An illustrative depiction of a dual‐crosslinked polymer network achieved with dynamic crosslinkers (blue) and covalent crosslinkers (red). ABSTRACT Creating artificial skin requires materials that can mimic the mechanical properties and structural integrity of natural skin.
Lilian Boton, Brett Leslie Pollard, Luke A. Connal +2 more
wiley +1 more source

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