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Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +295 more
wiley +1 more source

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel +18 more
wiley +1 more source

Andrew Lytle correspondence with Lula Ulrica Whitaker, 1934 February 4

, 1934
Letter from Andrew Lytle to Lula Ulrica Whitaker in response to a request from Whitaker for information about the Agrarian movement, in which Lytle describes the role of politics and economics in the birth of the Agrarian ...
Lytle, Andrew Nelson, 1902-1995
core +2 more sources

Brazilian South American geopolicy in the XXI Century

Revista Colección, 2017
The combination of material power critical mass, economic and political stability reached by Brasilia, as well as the existence of certain basic consents referring to foreign policy and security, seems to give Brazil roles and agendas of a regional power
Fabián C. Calle
doaj

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola +5 more
wiley +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen +17 more
wiley +1 more source

Conceptualizing Corporate Political Activity for Sustainability Governance—The CPA Cube

Business Strategy and the Environment, EarlyView.
ABSTRACT Sustainability transformations in the economy, and related public policy decisions, are highly contested, attracting business involvement. To better understand how business influence on government impacts the success or failure of sustainability governance efforts, this paper extends the literature on corporate political activity (CPA) by ...
Burkard Eberlein, Janina Grabs
wiley +1 more source

Donald Davidson correspondence with Lula Ulrica Whitaker, 1934 March 25

, 1934
Letter from Donald Davidson to Lula Ulrica Whitaker in response to a request from Whitaker for information about the Agrarian movement, in which Davidson describes the significance of I'll Take My Stand: The South and the Agrarian ...
Davidson, Donald, 1893-1968
core +2 more sources

Cardoso, Lula da Silva e o Oriente Médio

Meridiano 47, 2017
This article gathered data referring to the trips and agreements signed between Brazil and the Middle East in the administrations of Lula da Silva and Cardoso, and it was showed that Lula, in comparison to FHC, intensified the partnerships with the ...
Marcos Aurélio Guedes de Oliveira +2 more
doaj

From Capital to Green Innovation: Corporate Venture Capital as a Vehicle for Sustainable Organizational Learning

Business Strategy and the Environment, EarlyView.
ABSTRACT As increasing stakeholder pressure pushes firms to embed sustainability into their strategies, this study explores how corporate venture capital (CVC), a key corporate entrepreneurship instrument, supports corporate parents to learn from sustainable startups.
Louisa A. Müller, Julian D. Hüfner, Dominik K. Kanbach +2 more
wiley +1 more source

brasil
brazil
16. peace & justice

bolsa família
1. no poverty
8. economic growth