Results 171 to 180 of about 869,268 (413)

Submillimeter-Accurate 3D Lumbar Spine Reconstruction from Biplanar X-Ray Images: Incorporating a Multi-Task Network and Landmark-Weighted Loss [PDF]

open access: yesarXiv
Three-dimensional reconstruction of the spine under weight-bearing conditions from biplanar X-ray images is of great importance for the clinical assessment of spinal diseases. However, the current fully automated reconstruction methods only achieve millimeter-level accuracy, making it difficult to meet clinical standards.
arxiv  

DeepSPINE: Automated Lumbar Vertebral Segmentation, Disc-level Designation, and Spinal Stenosis Grading Using Deep Learning [PDF]

open access: yesarXiv, 2018
The high prevalence of spinal stenosis results in a large volume of MRI imaging, yet interpretation can be time-consuming with high inter-reader variability even among the most specialized radiologists. In this paper, we develop an efficient methodology to leverage the subject-matter-expertise stored in large-scale archival reporting and image data for
arxiv  

Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis

open access: yesArthritis &Rheumatology, EarlyView.
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley   +1 more source

Safety and effectiveness of the anti‐amyloid monoclonal antibody (mAb) drug lecanemab for early Alzheimer's disease: The pharmacovigilance perspective

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1352-1360, May 2025.
Abstract The development of humanized IgG1 anti‐amyloid monoclonal antibodies, such as lecanemab, provides a promising novel treatment pathway with potential disease‐modifying effects for patients with early Alzheimer's disease (AD). Lecanemab, which gained marketing approval by the United States Food and Drug Administration (US FDA) in July 2023, has ...
Amy Bobbins   +5 more
wiley   +1 more source

Efficacy of c-arm scopy-guided erector spinae plane block (ESPB) in postoperative pain control and reduction of opioid side effects in spinal instrumentation surgery

open access: yesRomanian Neurosurgery, 2020
Background: Spinal instrumentation surgery causes significant pain in patients. As a result, patients are exposed to excessive opioid use and the associated side effects, as well as prolonged hospital stay, resulting in economic burden.
Yasar Karatas   +6 more
doaj  

Congenital Lumbar Hernia [PDF]

open access: bronze, 1957
C. M. Lee, H Mattheis
openalex   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Instrumented Lumbar Corpectomy and Spinal Reconstruction Comparing rhBMP-2/Compression-Resistant Matrix, rhBMP-2/Absorbable Collagen Sponge/Ceramic Granules Mixture, and Autograft in Two Different Devices: A Study in Sheep [PDF]

open access: yes, 2016
Study Design. Fusion success with rhBMP-2 and autograft in titanium or PEEK corpectomy devices was evaluated in a sheep lumbar corpectomy model. The 6 treatment groups included titanium mesh or PEEK corpectomy devices filled with rhBMP-2 on a compression-
Mobasser, Jean-Piere   +3 more
core   +1 more source

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