Results 11 to 20 of about 124,017 (271)

Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1898-1909, December 2022., 2022
Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima, Satoshi Ito, Akira Kushida, Aki Abe, Wataru Motsuchi, David Verbel, Manu Vandijck, Geert Jannes, Ina Vandenbroucke, Katsumi Aoyagi   +9 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó   +16 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Is Closed-Suction Drainage Essential after Minimally Invasive Lumbar Fusion Surgery?: A Retrospective Review of 381 Cases [PDF]

Journal of Minimally Invasive Spine Surgery and Technique, 2017
Objective Closed suction drains have been widely used after lumbar fusion surgeries but with controversial evidence. The recent advances in the minimally invasive spine surgeries (MIS) lead to smaller dead space, lesser blood loss and fewer infections ...
Arvind Gopalrao Kulkarni, Ravish Shammi Patel   +1 more
doaj   +1 more source

Evolution of Percutaneous Endoscopic Lumbar Decompression [PDF]

Journal of Minimally Invasive Spine Surgery and Technique, 2019
Since Kambin and Hijikata firstly introduced the concept of percutaneous posterolateral lumbar discectomy, the technical improvement of percutaneous endoscopic lumbar discectomy (PELD) has been splendid in surgical approaches, design of optics and ...
Yong Ahn
doaj   +1 more source

Lumbar Interbody Fusion and Osteobiologics for Lumbar Fusion

Asian Spine Journal, 2022
Lumbar interbody fusion (LIF) is an excellent treatment option for a number of lumbar diseases. LIF can be performed through posterior, transforaminal, anterior, and lateral or oblique approaches. Each technique has its own pearls and pitfalls. Through LIF, segmental stabilization, neural decompression, and deformity correction can be achieved ...
Young-Hoon Kim, Kee-Yong Ha, Youn-Soo Kim, Ki-Won Kim, Kee-Won Rhyu, Jong-Beom Park, Jae-Hyuk Shin, Young-Yul Kim, Jun-Seok Lee, Hyung-Youl Park, Jaeryong Ko, Sang-Il Kim   +11 more
openaire   +3 more sources

From Stoop to Squat: A comprehensive analysis of lumbar loading among different lifting styles [PDF]

Frontiers in Bioengineering and Biotechnology (Biomechanics). 2021;9:769117, 2021
Lifting up objects from the floor has been identified as a risk factor for low back pain, whereby a flexed spine during lifting is often associated with producing higher loads in the lumbar spine. Even though recent biomechanical studies challenge these assumptions, conclusive evidence is still lacking.
arxiv   +1 more source

Parametric study of lumbar belts in the case of low back pain: effect of patients' specific characteristics [PDF]

Computational Biomechanics for Medicine, Springer International Publishing, pp.43-59, 2020, 2020
Objective: A numerical 3D model of the human trunk was developed to study the biomechanical effects of lumbar belts used to treat low back pain. Methods: This model was taken from trunk radiographies of a person and simplified so as to make a parametric study by varying morphological parameters of the patient, characteristic parameters of the lumbar ...
arxiv   +1 more source

The Influence of the Degree of Conformity to Terminological Principles and the Authority of the Creator of a Term on Establishment of Terms in Public Relations

Jezikoslovni zapiski, 2015
This article deals with the influence of the degree of conformity to terminological principles and the authority of their creators on the establishment of terms in public relations.
Katja Lumbar
doaj   +1 more source