Results 271 to 280 of about 617,988 (345)

Central Pathophysiology and Brain Network Changes Related to Camptocormia in Parkinson's Disease

Movement Disorders, EarlyView.
ABSTRACT Background Studies on brain connectivity offer important insights into the changes that occur in central network diseases such as Parkinson's disease (PD). Camptocormia, a condition characterized by abnormal flexion of the trunk, often occurs in advanced PD, but its underlying mechanisms are not yet clear.
Tauqeer Anjum, Jan Raethjen, Hao Ding, Nabin Koirala, Rüdiger Pryss, Robin Wolke, Chi Wang Ip, Günther Deuschl, Jens Volkmann, Nils G. Margraf, Muthuraman Muthuraman   +10 more
wiley   +1 more source

Adverse Impact of Smoking on Spine Fusion and Patient-Reported Outcomes: A Systematic Review and Meta-Analysis. [PDF]

Global Spine J
Arnold PM, Harrop JS, Mariscal G, Sasso RC, Steinmetz MP, Chaput CD, Jacobs WB, Witiw CD, O'Toole JE.   +8 more
europepmc   +1 more source

Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Inhibition of Nod‐like receptor protein 3 (NLRP3) inflammasome within the central nervous system (CNS) is a promising therapeutic target for the treatment of Parkinson's disease (PD). Objectives This phase 1b open‐label study was conducted in elderly healthy volunteers (HV) and PD patients.
Nicholas Clarke, Peter Thornton, Valérie Reader, Nicola Lindsay, Zsofia Digby, Bianca Mullen, Michelle Gorman, Eric Jacobson, Grant Langdon, Hilary Johnstone, Alistair Wheeler, Alan P. Watt   +11 more
wiley   +1 more source

The innovation of spinal endoscopy: one-hole bi-medium endoscopy for decompression and fusion in the treatment of lumbar degenerative diseases. [PDF]

Front Surg
Cui X, Li H, Jing X, Jia F, Liu X.
europepmc   +1 more source

Comparison of Two α‐Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism

Movement Disorders, EarlyView.
Abstract Background Seed amplification assays (SAAs) for misfolded α‐synuclein (syn) have shown inconsistent results in multiple system atrophy (MSA). Objective The objective of this study was to compare a novel syn SAA (synSAA) that distinguishes between Lewy body disease (LBD) and MSA syn‐seeds (Amprion‐SAA) with an LBD‐specific synSAA (IRCCS ...
Marcello Rossi, Carly M. Farris, Simone Baiardi, Giulia Giannini, Franco Magliocchetti, Luisa Sambati, Yihua Ma, Erica Vittoriosi, Giovanna Calandra‐Buonaura, Luis Concha‐Marambio, Piero Parchi   +10 more
wiley   +1 more source

Normality of sagittal spinal alignment parameters reveals evolutionary signals in healthy adults across five countries. [PDF]

Sci Rep
Hasegawa K, Watanabe K, Ohashi M, Hatsushikano S, Sardar ZM, Huec JCL, Bourret S, Kelly MP, Wong HK, Hey HWD, Liu G, Riahi H, Lenke LG.   +12 more
europepmc   +1 more source

Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial

Movement Disorders, EarlyView.
Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess, Jessika Suescun, Juan D. Martinez‐Lemus, Charles Green, Tia S. Thomas, Mohammad Shahnawaz, Emily Tharp, Nikunj B. Satani, Jerome G. Saltarrelli, Christopher Adams, Marie‐Francoise Doursout, Vanessa Thyne, Rula Abuamouneh, Elsa M. Rodarte, Sean I. Savitz, Timothy M. Ellmore   +15 more
wiley   +1 more source

Comparison of the clinical efficacy of percutaneous endoscopic lumbar interbody fusion through different surgical approaches: a retrospective study. [PDF]

J Orthop Surg Res
Feng Z, He Z, Zhu J, Fu C.
europepmc   +1 more source

A Biomarker‐Based Classification of Corticobasal Syndrome

Movement Disorders, EarlyView.
Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis, Alexander Maximilian Bernhardt, Endy Weidinger, Urban M. Fietzek, Alexander Jäck, Sabrina Katzdobler, Johannes Gnörich, Theresa Bauer, Nicolai Franzmeier, Robert Perneczky, German Imaging Initiative for Tauopathies (GII4T), Matthias Brendel, Johannes Levin, Günter U. Höglinger   +13 more
wiley   +1 more source

Comparison of clinical efficacy of two approaches for endoscopic lumbar fusion surgery in the treatment of single-segment lumbar spondylolisthesis. [PDF]

Front Surg
Li K, Lin H, Zhang Z, Meng X.
europepmc   +1 more source