Results 61 to 70 of about 390,913 (299)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Functional asymmetry of the spine in standing and sitting positions [Funkční asymetrie páteře vstoje a vsedě]

Acta Universitatis Palackianae Olomucensis. Gymnica, 2010
BACKGROUND: A sedentary lifestyle, together with functional asymmetry of the body, are potentially dysfunctional factors. OBJECTIVE: In this project, the authors are trying to identify the connections between a sedentary lifestyle and the amount of ...
Rafał Gnat, Patryk Kłaptocz, Maciej Biały   +2 more
doaj  

Relationships Between Muscle Activation and Thoraco-Lumbar Kinematics in Direction-Specific Low Back Pain Subgroups During Everyday Tasks

Biomechanics
Background/Objectives: The assessment of relationships between trunk muscle activity and thoraco-lumbar movements during sagittal bending has demonstrated that low back pain (LBP) subgroups (flexion pattern and active extension pattern motor control ...
Rebecca Hemming, Alister du Rose, Liba Sheeran, Valerie Sparkes   +3 more
doaj   +1 more source

Textiloma mimicking soft tissue tumor: an uncommon complication of posterior lumbar surgery

PAMJ Clinical Medicine, 2020
Textiloma (from Greek textile and ome = tumour) also called gossypiboma (from Latin Gossypium = cotton and Swahili boma = hiding place) is defined as the inadvertent retention of textile foreign body after surgical intervention leading to various ...
Inas El kacemi, Brahim El Mostarchid
doaj   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Comparison of postoperative complications and outcomes following primary versus revision discectomy: A national database analysis

Journal of Craniovertebral Junction and Spine
Background: Lumbar microdiscectomy is a surgical procedure that is frequently used in the treatment of symptomatic lumbar herniation. Differences in outcomes following primary and revision lumbar microdiscectomy have been previously studied, with reports
Ryan Hoang, Junho Song, Justin Tiao, Sarah Trent, Alex Ngan, Timothy Hoang, Jun S. Kim, Samuel K. Cho, Andrew C. Hecht, David Essig, Sohrab Virk, Austen D. Katz   +11 more
doaj   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

L5 spondylolysis increases segmental mobility at the cranial adjacent level without altering intervertebral disc contact pressure

Frontiers in Bioengineering and Biotechnology
ObjectiveWhile lumbar spondylolysis has been biomechanically associated with subsequent spondylolisthesis and disc degeneration, its implications on cranial adjacent segments remain unclear.
Zhilin Ge, Bingde Zhao, Xu Xu, Lin Chen, Dongzhu Liang, Qingyang Kang, Zibo Gao, Junhua Luo, Jiheng Zhan, Jianquan Chen, Bo Zhang   +10 more
doaj   +1 more source