Results 131 to 140 of about 73,788 (259)

A comparative study of Ommaya reservoir versus lumbar puncture for intrathecal chemotherapy in patients with leptomeningeal metastasis: a systematic review and meta-analysis. [PDF]

J Neurooncol
Zhang L, Feng M, Yang Y, Qi Z, Bihani P, Shah KS, Ong YX, Wang K, Cao Y, Li L, Gao Y.   +10 more
europepmc   +1 more source

A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain‐Inducing Nucleus Pulposus Cell Emergence

JOR SPINE, Volume 9, Issue 3, September 2026.
A porcine model of disc injury recapitulates key clinical, histological, and molecular features of human discogenic low back pain. Multi‐omics analyses identify a shift from notochordal cells to pain‐associated nucleus pulposus cells as a potential driver of disease progression. ABSTRACT Background Lower back pain (LBP) is one of the most common causes
Giselle Kaneda, Jacob T. Wechsler, Melissa Chavez, Julia Sheyn, Karandeep Cheema, Chushu Shen, Dante Rigo De Righi, Lixia Wang, Yin‐Chen Hsu, Pablo Avalos, Yibin Xie, Wafa Tawackoli, Candace Floyd, Debiao Li, Dmitriy Sheyn   +14 more
wiley   +1 more source

The Role of Fundoscopy Before Lumbar Puncture in Children with Suspected Meningitis. [PDF]

Eur J Pediatr
Friedman N, Kaplan O, Test G, Koppel JH, Altberg G, Cohen N, Levy N, Gil-Ad S, Cohen NK, Milshtein NY, Feldman HP, Mreisat H, Gimelraikh Y, Kimhi G, Yaniv LG, Jacob R.   +15 more
europepmc   +1 more source

Transgenic Conversion of Omega‐6 to Omega‐3 Fatty Acids via fat‐1 Reduces Obesity‐Related Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 3, September 2026.
We investigated whether transgenic conversion of omega‐6 to omega‐3 fatty acids mitigates obesity‐associated intervertebral disc (IVD) degeneration. Using fat‐1 mice on a high‐fat diet, we observed that endogenous omega‐3 production prevented diet‐induced disc pathology, metabolic dysfunction, and reduced systemic inflammation, indicating a protective ...
Shirley N. Tang, Kristin L. Lenz, Emma Shen, Collin Murray, Nikitha Ada, Sarada Prasad, Mohammed Kuziez, Farshid Guilak, Arin K. Oestreich   +8 more
wiley   +1 more source

Headache and Neurological Symptoms Following Lumbar Puncture in a Patient With a Ventriculoperitoneal Shunt. [PDF]

Cureus
Koenig N, Howell S, Kohli A, Shepherd J.
europepmc   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, Dmitriy Sheyn   +9 more
wiley   +1 more source

Ultrasound measurement of optic nerve sheath diameter pre and post lumbar puncture for prediction of postdural puncture headache. [PDF]

Sci Rep
Merzou F, Kunzmann AL, Janitschke D, Valdueza J, Landau B, Roemer S, Stolz E, Schappe L, Versace V, Kottackal S, Lochner P.   +10 more
europepmc   +1 more source

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

Muscle &Nerve, Volume 74, Issue 3, Page 692-697, September 2026.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler, Kush Mehta, Danica Sanders, Cathy Chin, Hannah Zivalic, Judith Carey, Alexandra McCaffrey, Pravin Pant, Carl Lewenhaupt, Sarah Luppino, Gabriel Jacobs, Shea Golden, Ryan Gifford, Erica Scirocco, Mackenzie Keegan, Munaf Hatem, Taravat Yazdanian, Sanem P. Uysal, Natalie Susco, Shauna Schwartzman, Karen Branch, Kathryn E. Hall, Joanna Barnas, Jenny Lam, Jennifer Hagar, Carol Ann Hannan, Sabrina Paganoni, James D. Berry, Mark Garret, Jennifer Scalia, Suma Babu   +30 more
wiley   +1 more source

The Utility of Point-Of-Care Ultrasound for Paediatric Lumbar Puncture: A Narrative Review. [PDF]

Emerg Med Australas
Trang J, Ku D, Snelling PJ.
europepmc   +1 more source

Processed EEG Monitoring During Pediatric Procedural Sedation: Correlation Between the Narcotrend Index and the Pediatric Sedation State Scale

Pediatric Anesthesia, Volume 36, Issue 9, Page 1126-1131, September 2026.
ABSTRACT Background Objective assessment of sedation depth in children undergoing procedural sedation while maintaining spontaneous breathing and protective reflexes can be challenging. Processed electroencephalogram (pEEG) monitoring systems such as the Narcotrend monitor may provide continuous information regarding the depth of sedation.
Hendryk Schneider, Daniel Matheisl, Martin Kuntz, Hans Fuchs   +3 more
wiley   +1 more source