Results 171 to 180 of about 130,855 (299)

Circadian Rhythm: Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This review offers a comprehensive overview of the mechanisms by which circadian rhythms modulate tissue homeostasis, alongside the associations between circadian disturbances and circadian rhythm‐related diseases. Furthermore, we offer insights into circadian rhythm‐regulating therapies, which may contribute to the development of novel strategies for ...
Kangkang Zha   +13 more
wiley   +1 more source

Clinical effects of arthroscopic-assisted uni-portal spinal surgery and unilateral bi-portal endoscopy on unilateral laminotomy for bilateral decompression in patients with lumbar spinal stenosis: a retrospective cohort study

open access: yesJournal of Orthopaedic Surgery and Research
Objective To investigate the clinical effectiveness of Arthroscopic-assisted Uni-portal Spinal Surgery (AUSS) in the treatment of lumbar spinal stenosis.
Fang Wang   +4 more
doaj   +1 more source

Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis

open access: yesBrain and Spine
Introduction: Lumbar spinal stenosis results in pain in the buttocks and/or legs due to reduced space in the spinal canal. MRI findings indicate that approximately 40 % of clinically diagnosed patients have multilevel stenosis.
Mikkel Ø. Andersen   +4 more
doaj   +1 more source

Is spinal stenosis assessment dependent on slice orientation? A magnetic resonance imaging study [PDF]

open access: yes, 2018
Introduction: Lumbar spinal stenosis (LSS) treatment is based primarily on the clinical criteria providing that imaging confirms radiological stenosis. The radiological measurement more commonly used is the dural sac cross-sectional area (DSCA).
Henderson, Lucy   +4 more
core  

Cardiovascular Morbidity in Patients Undergoing Successful Surgery for Primary Hyperparathyroidism

open access: yesClinical Endocrinology, Volume 103, Issue 5, Page 669-681, November 2025.
ABSTRACT Objective Although previous studies have shown reduced cardiovascular events following parathyroidectomy (PTX), it is unclear whether this extends to contemporary patients diagnosed and treated with milder disease than previously. The aim of this nation‐wide study was to determine the effect on cardiovascular events after PTX, and to ...
Martin Nilsson   +5 more
wiley   +1 more source

A Novel Intronic Variant in the KH3 Domain of HNRNPK Leads to a Mild Form of Au‐Kline Syndrome

open access: yesClinical Genetics, Volume 108, Issue 5, Page 576-581, November 2025.
Integrated genomic and epigenomic analyses, associated with functional studies, confirm the pathogenicity of a novel HNRNPK variant in Au‐Kline syndrome (AKS). Our study underscores the value of DNA methylation signatures in variant interpretation, enhancing accurate diagnosis and clinical management of rare neurodevelopmental disorders.
Maura Mingoia   +16 more
wiley   +1 more source

Inter- and Intraobserver Agreement of Morphological Grading for Central Lumbar Spinal Stenosis on Magnetic Resonance Imaging

open access: gold, 2015
Clemens Weber   +5 more
openalex   +1 more source

WITHDRAWN: A critical appraisal of clinical practice guidelines for the treatment of lumbar spinal stenosis

open access: gold, 2020
D.B. Anderson   +7 more
openalex   +1 more source

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