Results 271 to 280 of about 268,329 (333)

Loading and recovery behavior of the human lumbar spine under static flexion

, 2006
Guntulu Hatipkarasulu, Guntulu Hatipkarasulu   +1 more
openalex   +2 more sources

The Orthotic Effect of Functional Electrical Stimulation on Reactive Stepping for People With Incomplete Spinal Cord Injury

Artificial Organs, EarlyView.
This study evaluated the orthotic effect of functional electrical stimulation (FES) on reactive stepping in 16 participants with chronic, motor incomplete spinal cord injury (iSCI). Participants completed 10–20 trials of the Lean‐and‐Release test, with FES applied in half at random.
Matthew G. Heffernan, Jonguk Lee, Katherine Chan, Elizabeth L. Inness, Kei Masani, Kristin E. Musselman   +5 more
wiley   +1 more source

Chondromyxoid fibroma of the lumbar spine: is tumor recurrence to be expected after subtotal resection? Illustrative case. [PDF]

J Neurosurg Case Lessons
Le AQ, Bartanusz V, Floyd Ii JR, Gaub M, Nazarullah A, McGinity M.   +5 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Mechanical instability of the lumbar spine following intervertebral disc injury: a comparison of two injury methods. [PDF]

Int Biomech
Xiao F, Noort W, Lévénez J, Han J, van Dieën JH, Maas H.   +5 more
europepmc   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

Lumbosacral transitional vertebra alters the mobility of the lumbar spine on flexion-extension radiographs. [PDF]

Int Orthop
Kuoppala A, Määttä J, Hanhivaara J, Niinimäki J, Nevalainen M.   +4 more
europepmc   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh, Nathalie Vermeulen, Carolyn Ee, Helena Teede, Amanda J. Vincent   +4 more
wiley   +1 more source

Neuromodulation for Multifocal Pain: Successful Use of Spinal Cord Stimulation in Lumbar Spine Pain and Chronic Pancreatitis. [PDF]

Orthop Rev (Pavia)
Hasoon J, Orlando D, Chavez V, Viswanath O.   +3 more
europepmc   +1 more source