Results 291 to 300 of about 268,329 (333)

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, EarlyView.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

Association between serum uric acid levels and lumbar spine Z-scores in adults aged <50 years: A cross-sectional study. [PDF]

Metabol Open
Sun G, Zhou Y, Zhang P.
europepmc   +1 more source

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

The FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut, Danae Campos‐Melo, Michael J. Strong   +2 more
wiley   +1 more source

A study on the macro- and micro-dynamic characteristics of lumbar spine under different frequencies based on finite element analysis. [PDF]

Sci Rep
Zhang B, Xue R, Yuan J, Yang Q.
europepmc   +1 more source

Concurrent changes in disability caused by back and neck pain after lumbar spine surgery: a multigroup trajectory analysis. [PDF]

J Orthop Surg Res
Koivunen K, Lintuaho R, Arokoski J, Pernaa K, Saltychev M.   +4 more
europepmc   +1 more source

Incidental Durotomy Significantly Increases the Risk of Postoperative Infection Following Lumbar Spine Surgery for Degenerative Conditions: A Systematic Review and Meta-analysis. [PDF]

Int J Spine Surg
Babasiz T, Leyendecker J, Weber M, Egenolf P, Hampl J, Yagdiran A, Eysel P, Sircar K.   +7 more
europepmc   +1 more source

Regular walking is associated with greater lumbar spine bone mineral density in elderly men with adequate vitamin D levels. [PDF]

Sci Rep
Zouch M, Zribi A, Ali WI.
europepmc   +1 more source

The Effects of Variation in Physical Activity and Spinal Loading on Trunk Muscle Endurance and Lumbar Spine Function

Sibson, Benjamin
openalex   +1 more source

Automated lumbar spine segmentation in MRI using an enhanced U-Net with inception module and dual-output mechanism. [PDF]

Sci Rep
Silveira JT, S G, Kundapur PP.
europepmc   +1 more source