Is Sacral Extension a Risk Factor for Early Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery? [PDF]
, 2020 Study designRetrospective cohort study.PurposeTo investigate the role of sacral extension (SE) for the development of proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) surgery.Overview of literatureThe development of PJK is ...
Ames, Christopher +10 more
core
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Radiation Dose and Risk Assessment to Patients During Thoraco-Lumbar and Lumbar Spine X-ray Procedures [PDF]
, 2023 Buhari Samaila +2 more
openalex +1 more source
Advanced Science, EarlyView.Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source
A Rare Presentation of Primary Hydatid Cyst in an Adolescent – A Case Report
Pakistan Journal of Medicine and Dentistry, 2020 The aim of this case study was to report a very uncommon and rarely seen, but serious condition, involving spine. Hydatid cyst is caused by Echinococcus granulosus mainly. It is rarely found in spine, lumbar spine is least commonly involved in spine.
Asad Aziz, Javeria Junaid, Imtiaz Hashmi
doaj +1 more source
Measuring spinal motion in rowers: the use of an electromagnetic device. [PDF]
, 2000 Accepted ...
Bull, AM, McGregor, AH
core +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Functional outcome following direct repair or intervertebral fusion for adolescent spondylolysis : a systematic review [PDF]
, 2012 A systematic review of the literature was performed to establish whether direct repair of the pars defect or intervertebral fusion achieves better Oswestry Disability Index scores in adolescent spondylolysis or low-grade spondylolisthesis.
Cooke, Stephen J., Westacott, Daniel J.
core +1 more source
Current and Future Applications of the Kambin’s Triangle in Lumbar Spine Surgery [PDF]
, 2022 Romaric Waguia +3 more
openalex +1 more source
Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD
Advanced Science, EarlyView.Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du +6 more
wiley +1 more source