Results 231 to 240 of about 175,035 (289)

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes   +5 more
wiley   +1 more source

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu   +2 more
wiley   +1 more source

Biomechanical, Structural, and Composition Characterization of the Vertebra‐Disc Interface

open access: yesJOR SPINE, Volume 9, Issue 4, December 2026.
ABSTRACT Background The spinal endplate region consists of the cartilage endplate (CEP), bony endplate (BEP), and subchondral trabecular bone (STB). Although this region is often involved in vertebral fractures and disrupted with disc degeneration, the biomechanics of these tissues are incompletely understood. The goal of this study was to characterize
Neilesh R. Frings   +5 more
wiley   +1 more source

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

open access: yesThe Anatomical Record, Volume 309, Issue 11, Page 3257-3275, November 2026.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban   +3 more
wiley   +1 more source

Enhanced Transmit Efficiency of a Loop Array Combined With Out‐of‐Phase Passive Dipoles for Thoracic Spinal Cord MRI at 7T

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 5, Page 2539-2552, November 2026.
ABSTRACT Purpose The design of radiofrequency (RF) coils tailored for the target anatomy is necessary to overcome the transmit field homogeneity and penetration issues at Ultra‐High‐Field (UHF). For the spinal cord, the optimal design has not yet been determined. This work intends to demonstrate the added value of a pair of passive dipoles placed under
Hugo Amat   +10 more
wiley   +1 more source

Gastroschisis‐Like Defect in a Crossbred Bovine Calf: Anatomical, Clinical and Surgical Perspectives

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A gastroschisis‐like defect was observed in a one‐day‐old, crossbred bovine calf with evisceration of the pyloric abomasum and small intestine, likely resulting from prenatal rupture of an omphalocele. The calf presented with lethargy, hypothermia and metabolic derangements, along with elevated renal biomarkers.
Mohammad Raguib Munif   +1 more
wiley   +1 more source

Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub   +3 more
wiley   +1 more source

Acute kidney injury in a dog after ingestion of homemade modelling dough containing cream of tartar (potassium bitartrate)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary A 16‐month‐old, male, neutered cocker spaniel developed gastrointestinal signs following ingestion of a homemade modelling dough containing cream of tartar. Blood biochemistry (29 hours post‐ingestion) showed elevated creatinine, urea and symmetric dimethylarginine (SDMA).
Fiona Adam, Nicola Bates
wiley   +1 more source

Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 12, Page 2188-2195, November 2026.
ABSTRACT Objectives To quantify the discrepancy between anatomical and motor levels in foetuses with open spinal dysraphism and identify prenatal factors associated with this difference. We also examined associations between anatomical level and ultrasound findings. Design Retrospective observational study.
Silvia Arévalo   +8 more
wiley   +1 more source

New Results From the Pre‐Pottery Neolithic Site of Al Uyaynah, Tabuk, in Northwestern Saudi Arabia

open access: yesArabian Archaeology and Epigraphy, Volume 37, Issue 1, Page 182-206, November 2026.
ABSTRACT Al Uyaynah is a low sandstone mound on an alluvial plain, long known for its extensive surface remains of stone‐built circular and rectangular structures. Following test excavations in 2012, more detailed excavation was undertaken in 2016 within one of the largest rectangular stone structures.
Khalid Alasmari   +6 more
wiley   +1 more source

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