Results 301 to 310 of about 360,246 (383)

Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb

Experimental Physiology, EarlyView.
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet, Maria Papaiordanidou, Nicolas Amiez, Ioannis Amiridis, Jean‐Pierre Quenot, Alain Martin   +5 more
wiley   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

5‐HT7 antagonists confer analgesia via suppression of neurotrophin overproduction in submucosal nerves of mouse models with visceral hypersensitivity

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram of intestinal nerve abnormality underlying the mechanisms of visceral hypersensitivity. In physiological conditions with normal sensation, enteric neurons are situated in the submucosal and myenteric plexuses, and the spinal afferent fibres ramify within the enteric plexus. However, serotonin/5‐hydroxytryptamine
Tzu‐Yi Lee, Yu‐Hsuan Lin, Wen‐Ying Chang, Li‐Yu Lin, Che‐Feng Chang, Wei‐Ting Kuo, Chia‐Hung Tu, Ming‐Shiang Wu, Ling‐Wei Hsin, Linda Chia‐Hui Yu   +9 more
wiley   +1 more source

Impact of Habitual Flexion on Bone Formation After Spinal Fusion Surgery: An In Silico Study

JOR SPINE, Volume 8, Issue 3, September 2025.
Lumbar spinal fusion is an effective treatment for spinal conditions, but non‐union remains a challenge due to unfavorable mechanical signals at the fusion site. This study used a computational model to investigate how habitual flexion loading affects bone fusion, finding that hybrid (compression + flexion) loading led to greater bone formation ...
Siddarth Ananth Swaminathan, Nima Taheri, Luis Becker, Matthias Pumberger, Hendrik Schmidt, Sara Checa   +5 more
wiley   +1 more source

Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain

JOR SPINE, Volume 8, Issue 3, September 2025.
This study aims to validate an underutilized canine preclinical model of discogenic back pain model by deep phenotyping several structural and pain associated outcomes with novel findings in the areas of RNA sequencing and whole patch clamp of canine dorsal root ganglion neurons.
Mary K. Heimann, Shirley N. Tang, Gilian Gunsch, Kyle Kuchynsky, Brett Klamer, Fangli Zhao, Megan Co, Maciej Pietrzak, Justin Richards, Jake Klausner, Adam Smith, Kaitlyn Cimney, Sara McBride‐Gagyi, Brad Youngblood, Kara Corps, Candice Askwith, Benjamin A. Walter, Sarah A. Moore, Devina Purmessur   +18 more
wiley   +1 more source

Sexual Dimorphism and Population-Specific Sex Estimation Equations Using Morphometric Analysis of Dry Lumbar Vertebrae in a Northeastern Thais

Worrawit Boonthai, Akkaranai Kwanyou, Sarittaporn Puntawangkoon, Rusna Waehama, Chanasorn Poodendaen, Supatcharee Arun, Arada Chaiyamoon, Sitthichai Iamsaard, Suthat Duangchit   +8 more
openalex   +1 more source

Measurement of the kinematics of the lumbar spine in vivo

, 2001
Allen, R., Nixon, M.S., Zheng, Y.
core