Results 161 to 170 of about 11,360 (208)

Efficacy and tolerability of artemether–lumefantrine and pyronaridine-artesunate for uncomplicated Plasmodium falciparum malaria in Niger

Alhousseini D, Maiga ML, Fofana B, Traore A, Brah S, Daou M, Ibrahim A, Abdourahamane Y, Sagara I, Dicko A, Djimde A, Eric A.   +11 more
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Gender differences in pharmacokinetics of lumefantrine and its metabolite desbutyl‐lumefantrine in rats

Biopharmaceutics and Drug Disposition, 2012
ABSTRACTLumefantrine has been reported to be mainly bio‐transformed by cytochrome P450 isozyme 3A4 to desbutyl‐lumefantrine (DLF) in human liver microsomes. Since CYP3A is expressed in a sex specific manner in rats, it could be expected that the pharmacokinetics of lumefantrine would be changed in male rats compared with those in female rats.
, Wahajuddin, Sheelendra Pratap, Singh, Girish Kumar, Jain   +2 more
exaly   +3 more sources

Artemether-Lumefantrine: An Option for Malaria

Annals of Pharmacotherapy, 2012
Objective: To review the pharmacology, pharmacokinetics, safety, and efficacy of artemether-lumefantrine for the treatment of Plasmodium falciparum malaria. Data Sources: English-language articles indexed in PubMed (1947-November 2011)
Travis King
exaly   +3 more sources

Enantioselective in vitro ADME, absolute oral bioavailability, and pharmacokinetics of (−)-lumefantrine and (+)-lumefantrine in mice

Xenobiotica, 2020
Lumefantrine (LFN) is a chiral antimalarial drug. Enantioselective in vitro attributes and absolute oral pharmacokinetics for (-)-LFN and (+)-LFN have been characterized in mice. No stereoselectivity was seen with either of the enantiomers when compared with rac-LFN in the executed in vitro studies (solubility, metabolic stability, protein binding ...
Bhavesh Babulal Gabani, Abhishek Dixit, Vinay Kiran, Ram Murthi Bestha, Balaji Narayanan, Nuggehally R. Srinivas, Ramesh Mullangi   +6 more
openaire   +2 more sources

Artemether/lumefantrine

Reactions Weekly, 2022
  +4 more sources

Artemether/lumefantrine

Reactions Weekly, 2023
  +4 more sources

Lumefantrine

2021
openaire   +2 more sources

Artemether/lumefantrine

Reactions Weekly, 2021
openaire   +1 more source

Artemether/lumefantrine

Reactions Weekly, 2018
  +4 more sources

Artemether/lumefantrine

Reactions Weekly, 2020
openaire   +2 more sources