Results 51 to 60 of about 60,818 (316)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Synergy of Architectural Lighting with Sustainable City Development—A Case Study
BuildingsDesigning the floodlighting of objects in the context of improving the night image of the city is a very complex task, requiring not only a time commitment but also precise analysis and innovative solutions.
Rafał Krupiński
doaj +1 more source
Annals of Indian Academy of Neurology, 2013 Context: Visual evoked potentials are useful in investigating the physiology and pathophysiology of the human visual system. Flash visual evoked potential (FVEP), though technically easier, has less clinical utility because it shows great variations in ...
Senthil Kumar Subramanian +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Ensaio de caracterização dos campos visuais de crianças em salas de aula: identificação dos componentes arquitetônicos de maior influência [PDF]
, 2011 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Arquitetura e Urbanismo, Florianópolis, 2011A sala de aula é um dos ambientes nos quais as crianças passam grande parte do tempo e ...
Vásquez, Natalia Giraldo
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Experiences with Luminal in Epilepsy [PDF]
The American Journal of the Medical Sciences, 1920 n ...
openaire +3 more sources
Target recognitions in multiple camera CCTV using colour constancy [PDF]
, 2013 People tracking using colour feature in crowded scene through CCTV network have been a popular and at the same time a very difficult topic in computer vision.
Merfort, Christian +8 more
core +1 more source