Results 141 to 150 of about 1,840 (258)

Atmospheric systems drive spatiotemporal divergence of dust and moisture changes across Asia over the past 130,000 years. [PDF]

open access: yesSci Adv
Li G   +35 more
europepmc   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai   +13 more
wiley   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

open access: yesiMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia   +11 more
wiley   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

open access: yesiMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie   +12 more
wiley   +1 more source

New evidence for Early Pleistocene use of fire at Wonderwerk Cave (South Africa). [PDF]

open access: yesPLoS One
Marin-Monfort MD   +11 more
europepmc   +1 more source

Shared foraging behaviors between hyenas and hominins in the Middle Paleolithic Levant: New evidence from Geula Cave, Israel

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT While competition with large carnivores is likely to have shaped Middle Paleolithic hominins' subsistence behavior, palimpsested human and carnivore accumulations render the signal challenging to isolate. This study presents a detailed zooarchaeological and taphonomic analysis of a non‐anthropogenic faunal assemblage from a MIS 5 (~130–80 ka ...
Meir Orbach   +4 more
wiley   +1 more source

Monumental rock art illustrates that humans thrived in the Arabian Desert during the Pleistocene-Holocene transition. [PDF]

open access: yesNat Commun
Guagnin M   +16 more
europepmc   +1 more source

Integrating ZooMS and taphonomy further highlights differential processing of animal and Neandertal carcasses in the Quina Mousterian at Les Pradelles (Marillac‐le‐Franc, southwest France)

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT The cave of Les Pradelles (Marillac‐le‐Franc, France) was repeatedly visited by Neandertals ~55 000 years ago and is a key site in discussions of Neandertal cannibalism. Excavations between 1967 and 1980 (Vandermeersch) and between 2001 and 2013 (Maureille/Mann) produced a rich faunal assemblage (>20 000 bones), alongside Quina Mousterian ...
Pauline Raymond   +7 more
wiley   +1 more source

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