Results 1 to 10 of about 15,619 (184)

A dual-quenched ECL immunosensor for ultrasensitive detection of retinol binding protein 4 based on luminol@AuPt/ZIF-67 and MnO2@CNTs

Journal of Nanobiotechnology, 2021
Background Retinol binding protein 4 (RBP4) has been regarded as an important serological biomarker for type 2 diabetes mellitus (T2DM). Hence, the construction of a highly sensitive detection method for RBP4 is the key to early prevention and ...
Wei Gong, Suqing Yang, Fen Zhang, Fengshun Tian, Junman Chen, Zhigang Yin, Shijia Ding, Wei Yang, Rong Luo   +8 more
doaj   +1 more source

Can Luminol Be a Fluorophore? [PDF]

Journal of Fluorescence, 2019
In this work, we report a new chemiluminescence system using bis-(2,4,6-trichlorophenyl) oxalate (TCPO) with hydrogen peroxide and luminol as fluorophore. The intense chemiluminescence reaction here described was fully investigated and it was determined that this fluorescent system has two strong light emissions at 440 and 490 nm, respectively.
Barroso, M. Fátima, Silva, Rui J. A., Moreira, Sérgio F., Rodrigues, Sofia S., Gonçalves, Helena M. R., Duarte, Abel J.   +5 more
openaire   +3 more sources

FEATURES OF LUMINOL- AND LUCIGENIN-INDUCED CHEMILUMINESCENCE OF NEUTROPHILIC GRANULOCYTES IN PATIENTS WITH CHRONIC RHINOSINUSITIS

Медицинская иммунология, 2014
Studies of functional activity of neutrophilic granulocytes from patients with chronic rhinosinusitis was performed using luminol- or lucigenin-dependent chemiluminescence. We have revealed increased production of reactive oxygen species (ROS) both under
O. A. Kolenchukova, A. A. Savchenko, S. V. Smirnova   +2 more
doaj   +1 more source

Luminol immobilized graphite electrode as sensitive electrochemiluminescent sensor for the detection of hydrogen peroxide

Sensors International, 2020
The present work, presents the Luminol immobilized electrochemiluminescence (ECL) for the detection of hydrogen peroxide. Herein, the ECL behavior of luminol immobilized on graphite as a paste electrode has been studied in nearly neutral solution (pH = 8)
Rahat Nawaz, Tahir Rasheed, Muhammad Bilal, Saadat Majeed, Zahid Iqbal, Taniya Iqbal, Fahad Ali   +6 more
doaj   +1 more source

Localized Accumulation of Tri‐n‐Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis

Angewandte Chemie, EarlyView.
Here, we enhance the electrochemiluminescence imaging of cellular spheroids using [Ru(bpy)3]2+/TPrA chemistry. Our strategy, which involves pre‐incubation with TPrA, enables high‐resolution, long‐term visualization of cellular spheroids without phototoxicity.
Vanshika Gupta, Megan L. Hill, Samuel P. Nortz, Yashvi Choudhary, Ashutosh Rana, Jeffrey E. Dick   +5 more
wiley   +2 more sources

Electrochemically Generated Luminescence of Luminol and Luciferin in Ionic Liquids

ChemElectroChem, 2023
Electrochemiluminescence (ECL) is the generation of light triggered by an electrochemical reaction. ECL has been extensively studied in solvent‐based electrolytes, but there is a lack of data on using electrode reactions to populate an excited‐state ...
Mattia Belotti, Dr. Mohsen M. T. El‐Tahawy, Dr. Nadim Darwish, Prof. Dr. Marco Garavelli, Dr. Simone Ciampi   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Advances in the construction and application of chemiluminescence probes

Nantong Daxue xuebao. Ziran kexue ban, 2022
In the chemiluminescence process, when the luminescent system and the response substrate undergo a chemical reaction, the dye molecules in the system are excited by the chemical energy generated by the chemical reaction and generate light signals.
FENG Yurong; XU Shuai; HUAN Shuangyan; YUAN Lin; ZHANG Xiaobing
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source