Results 51 to 60 of about 15,619 (184)

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Sensitive Detection of Biomarker in Gingival Crevicular Fluid Based on Enhanced Electrochemiluminescence by Nanochannel-Confined Co₃O₄ Nanocatalyst

Biosensors
The sensitive detection of inflammatory biomarkers in gingival crevicular fluid (GCF) is highly desirable for the evaluation of periodontal disease. Luminol-based electrochemiluminescence (ECL) immunosensors offer a promising approach for the fast and ...
Changfeng Zhu, Yujiao Zhao, Jiyang Liu
doaj   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

The Chemiluminescence of Acyl Luminols [PDF]

Bulletin of the Chemical Society of Japan, 1966
Abstract From a study of the chemiluminescence spectra of acyl luminols (e.g., 3-acetylaminophthalhydrazide, 3-propanoylaminophthalhydrazide and 3-undecenoylaminophthalhydrazide) and of the corresponding fluorescence spectra of the reaction products, it is tentatively assumed that the emitting species of the chemiluminescence of acyl ...
Yoshimori Omote, Takeo Miyake, Seiya Ohmori, Noboru Sugiyama   +3 more
openaire   +1 more source

Cortical‐Hypothalamic Assembloids Uncover the Cortical Regulation of Hypothalamic Responses to Fatty Acid

Cell Proliferation, EarlyView.
By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao, Xiaowen Du, Qi Chen, Wenxin Mu, Shuning Lou, Xu Zhang, Min Xu, Jiting Li, Yuxuan Guo, Wanying Zhu, Yan Liu   +10 more
wiley   +1 more source

Evaluation of antiradical assays used in determining the antioxidant capacity of pure compounds and plant extracts

Química Nova, 2014
The efficiency of the chemiluminescence luminol method and colorimetric DPPH and ABTS methods in evaluating the antiradical capacity of pure compounds and plant extracts with antioxidant potential is compared.
Sandro de Oliveira, Glalci Alves de Souza, Camila Rodrigues Eckert, Thuany Alves Silva, Edmar Silva Sobral, Oriana Aparecida Fávero, Marcelo José Pena Ferreira, Paulete Romoff, Wilhelm Josef Baader   +8 more
doaj   +1 more source

Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann, Cedric Wilden, Leticia Prates‐Roma, Matthias W. Laschke, Emmanuel Ampofo, Selina Wrublewsky   +5 more
wiley   +1 more source

Chemiluminescence activity of neutrophil granulocytes under the influence of magnetic nanoparticles of ferrihydrite (in vitro)

Медицинская иммунология, 2020
The article presents the results of studying and evaluating the impact of magnetic nanoparticles of ferrihydrite on neutrophil granulocytes in human blood (in vitro) in order to determine their bio compatibility and eco toxicity.
O. A. Kolenchukova, S. V. Stolyar, V. P. Ladygina, E. A. Biryukova   +3 more
doaj   +1 more source

Regulation of the Yersinia pseudotuberculosis Type III Secretion System by the CpxAR Two‐Component System

Molecular Microbiology, EarlyView.
Host tissue cues including temperature, oxygen, and iron availability regulate expression of the Yersinia type III secretion system (T3SS) master regulator LcrF. We found that CpxR inhibits LcrF through an indirect, multi‐factorial mechanism and identified the osmolarity‐sensing OmpR/EnvZ system as an additional regulator of LcrF, highlighting ...
Karen Hug, Erin Mettert, Melissa Estrada Escobar, Cristina Vargas Vazquez, David Balderas, Sarvind Tripathi, Laya Ashley, Patricia J. Kiley, Victoria Auerbuch   +8 more
wiley   +1 more source

Enhanced Electrochemiluminescence of Luminol and-Dissolved Oxygen by Nanochannel-Confined Au Nanomaterials for Sensitive Immunoassay of Carcinoembryonic Antigen

Molecules
Simple development of an electrochemiluminescence (ECL) immunosensor for convenient detection of tumor biomarker is of great significance for early cancer diagnosis, treatment evaluation, and improving patient survival rates and quality of life.
Weibin Li, Ruliang Yu, Fengna Xi
doaj   +1 more source