Results 41 to 50 of about 5,055 (256)
Some Exact Solutions to Generalized Kadomtsev-Petviashvili Equation
Advances in Mathematical Physics, 2022 Most of the papers have explored the interactions between solitons with a zero background, while reports about exact solutions for nonzero background are rare.
Bao Wang, Zhiqiang Chen
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Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Evolution of lump solutions for the KP equation [PDF]
Wave Motion, 1996 Abstract The two (space)-dimensional generalisation of the Korteweg-de Vries (KdV) equation is the Kadomtsev-Petviashvili (KP) equation. This equation possesses two solitary wave type solutions. One is independent of the direction orthogonal to the direction of propagation and is the soliton solution of the KdV equation extended to two space ...
Minzoni, A. A., Smyth, N. F.
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
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Lump and rogue wave solutions to (1+1)-dimensional evolution equations
Partial Differential Equations in Applied Mathematics, 2022 In this paper, we study lump solutions and rogue wave solutions for three (1+1)-dimensional nonlinear dynamic systems. By applying the Hirota direct method, lump and rogue wave solutions are presented with the aid of symbolic computations.
Yuan Zhou
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Lump solutions in SFT. Complements
, 2011 Recently a possible violation of the equation of motion for the recently proposed lump solutions in open SFT has been pointed out in the literature. In this paper we argue that, when the issue is considered in the appropriate mathematical setting of distribution theory, no violations to the equation of motion occur.
Bonora, L., Giaccari, S., Tolla, D. D.
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Mixed lump-kink solutions to the BKP equation
Computers & Mathematics with Applications, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jian-bing Zhang, Wen-Xiu Ma
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