Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer
Neoplasia, 2017 Claudin-low breast cancer (CLBC) is a poor prognosis molecular subtype showing stemness and mesenchymal features. We previously discovered that deletion of a Notch signaling modulator, Lunatic Fringe (Lfng), in the mouse mammary gland induced a subset of
Wen-Cheng Chung +2 more
exaly +4 more sources
Neoplasia, 2014 Elevated Notch ligand and receptor expression has been associated with aggressive forms of prostate cancer, suggesting a role for Notch signaling in regulation of prostate tumor initiation and progression.
Shubing Zhang +2 more
exaly +4 more sources
The West Riding Lunatic Asylum Medical Reports: the precursor of Brain? [PDF]
Brain, 2023 First published in 1878, Brain: A Journal of Neurology is generally considered to be the world’s first neuroscientific journal. However, this claim might be challenged since the West Riding Lunatic Asylum Medical Reports, another journal with significant
Larner AJ.
europepmc +2 more sources
Thematic Analysis of Laxmi Prasad Devkota’s Poem “The Lunatic”
International Research Journal of MMC, 2022 A literary text can be analyzed through numerous perspectives, and a thematic analysis stands as one of the perennial perspectivespractised in analyzing poetry.
L. Sharma
semanticscholar +2 more sources
Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance
eLife, 2017 Hippocampal neural stem cells (NSCs) integrate inputs from multiple sources to balance quiescence and activation. Notch signaling plays a key role during this process.
Fatih Semerci +8 more
doaj +2 more sources
Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
Molecular Oncology, 2018 Metastasis is the leading cause of death in patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonisation are poorly understood.
Martin Del Castillo Velasco‐Herrera +8 more
doaj +2 more sources
Driven to Insanity: Marital Cruelty and the Female Patients at the Fremantle Lunatic Asylum, 1858-1908 [PDF]
Limina: A Journal of Historical and Cultural Studies, 2019 In nineteenth-century Fremantle, marital cruelty (domestic violence) could lead to a woman’s assessment of ‘insanity’ and result in incarceration in the Fremantle Lunatic Asylum.
Alexandra Wallis
doaj +1 more source
Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe [PDF]
bioRxiv, 2023 Tommaso Ristori +11 more
semanticscholar +2 more sources
Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis
eLife, 2018 Notch signalling maintains stem cell regeneration at the mouse intestinal crypt base and balances the absorptive and secretory lineages in the upper crypt and villus.
Preetish Kadur Lakshminarasimha Murthy +10 more
doaj +2 more sources
Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment. [PDF]
Stem Cell Reports, 2023 Negri VA +8 more
europepmc +2 more sources