Results 141 to 150 of about 2,224,563 (253)

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Generalized granuloma annulare associated with lung adenocarcinoma: a case report. [PDF]

Front Med (Lausanne)
Cai Y, Tang H.
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Synchronous Lobular Breast Cancer and Lung Adenocarcinoma: Α Case Report. [PDF]

Cureus
Pantelidou V, Perdikakis E, Eleftheriadis E, Lampridis S, Tsantila I, Permekerlis A.   +5 more
europepmc   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Correlation between E2F7 overexpression and immune infiltration in lung adenocarcinoma. [PDF]

Discov Oncol
Gao X, Zhao C, Wang S, Li J.
europepmc   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Identifying expression and DNA methylation biomarkers for lung adenocarcinoma risk in East Asia. [PDF]

J Natl Cancer Inst
Chen TY, Chien LH, Jiang SS, Choi J, Hung HH, Hsiao CF, Shi J, Blechter B, Breeze CE, Chang GC, Chen KY, Tsai YH, Su WC, Huang MS, Chen YM, Wen YF, Chen CY, Wang CL, Tsai FY, Chen HL, Hsieh WS, Lin HC, Wang LH, Chen CJ, Yang PC, Chen CY, Rothman N, Chanock SJ, Lan Q, Chang IS, Hsiung CA.   +30 more
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Lung microbiota analysis in early-stage lung adenocarcinoma. [PDF]

Microbiol Spectr
Sun K, Li B, Zhang C, Zhou K, Zheng Z, Gao C, Lin Y, Zhang N, Wang Z, Li J, Song L, Liang N, Liu Z.   +12 more
europepmc   +1 more source