Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
On the proper treatment of pathologies in biomedical ontologies [PDF]
, 2005 In previous work on biomedical ontologies we showed how the provision of formal definitions for relations such as is_a and part_of can support new types of auto-mated reasoning about biomedical phenomena.
Kumar, Anand, Smith, Barry
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Erratum to: Development of a nomogram combining clinical staging with 18F-FDG PET/CT image features in non-small-cell lung cancer stage I–III [PDF]
, 2016 Marie-Charlotte Desseroit +7 more
openalex +1 more source
Utility of PET-CT in non-small cell lung cancer clinical stage IB-IIA according to AJCC 8th edition staging system: an alternative to invasive mediastinal staging? [PDF]
, 2021 Agustín Buero +6 more
openalex +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Staging lung cancer: role of endobronchial ultrasound
Lung Cancer: Targets and Therapy, 2014 Terunaga Inage, Takahiro Nakajima, Ichiro Yoshino Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan Abstract: Accurate staging is the first step in the management of lung cancer.
Inage T, Nakajima T, Yoshino I
doaj
Predictors of distress among patients undergoing staging investigations for suspected colorectal and lung cancer [PDF]
, 2020 Anne Miles, Ruth Evans, Stuart A. Taylor
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Physiologic 18F-FDG muscle uptake in severe COPD: Implications for accurate lung cancer staging. [PDF]
Respirol Case Rep, 2023 Yoshida Y +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Economic Evaluation of Positron Emission Tomography (PET) in Non Small Cell Lung Cancer (NSCLC), CHERE Working Paper 2007/6 [PDF]
Background: There are several perceived benefits from introducing positron emission tomography (PET) scanning into the staging of non small lung cancer (NSCLC).
Alex Bird +2 more
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